Results 31 to 40 of about 2,511 (152)

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

“The word ‘Machu Picchu’ makes me very uncomfortable”: Racialized Latinidades in Spanish Higher Education Institutions

Migraciones
The paper examines the racialization processes experienced by a group of university students identified as Latin American, Latino, and/or Afro-Latin American in Spain.
Glenda Vaillant-Cruz, Antonia Olmos Alcaraz, Beatriz Padilla   +2 more
doaj   +1 more source

The lived class and racialization – histories of ‘foreign workers’ children’s’ school experiences in Denmark

Nordic Journal of Studies in Educational Policy, 2021
In recent years, the Danish education context has seen an increased concern about underperforming students with migratory histories (particularly students perceived as non-Western descendants) in the political and pedagogical discourses. There seem to be
Jin Hui Li
doaj   +1 more source

Introduction: Cultural Constructions of Race and Racism in the Middle East and North Africa / Southwest Asia and North Africa

Lateral, 2021
In recent years, scholars in the fields of cultural studies, American studies, history, ethnic studies, and Middle East area studies have approached questions of race and racism in this geographic region with renewed critical vigor.
Rayya El Zein
doaj   +1 more source

Real‐World Investigation of Satralizumab in Patients With Neuromyelitis Optica Spectrum Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Satralizumab, a monoclonal antibody targeting the interleukin‐6 receptor, has demonstrated efficacy in clinical trials for neuromyelitis optica spectrum disorder (NMOSD). However, its real‐world effectiveness and safety compared to conventional immunosuppressive therapies remain uncertain.
Li‐Tsung Lin, Hui‐An Lin, Sheng‐Feng Lin   +2 more
wiley   +1 more source

The property functions of whiteness and Swedishness – a case study of race reputation and status in urban education

Nordic Journal of Studies in Educational Policy, 2021
This paper examines the property functions of whiteness in urban educational practices in Sweden. Whiteness can be understood as racial privilege and racialized knowledge.
Osa Lundberg
doaj   +1 more source

Applying an Ethical Lens to the Treatment of People With Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The practice of neurology requires an understanding of clinical ethics for decision‐making. In multiple sclerosis (MS) care, there are a wide range of ethical considerations that may arise. These involve shared decision‐making around selection of a disease‐modifying therapy (DMT), risks and benefits of well‐studied medications in comparison to
Methma Udawatta, Farrah J. Mateen
wiley   +1 more source

Transgressive-racialization: a collective refusal of racial governance

Frontiers in Education
This analysis introduces transgressive-racialization as a praxis for resisting race’s structural imposition in U.S. schools. Drawing on Kantian notions of apperception, Althusser’s theory of interpellation, and Omi and Winant’s racial formation theory ...
Jonathan Pérez
doaj   +1 more source

Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi, Caroline Gochanour, Seung Ho Choi, Hyunkeun Cho, Chelsea Caspell‐Garcia, Christopher Coffey, Michael Brumm, David‐Erick Lafontant, Yuge Xiao, Thomas Tropea, John Seibyl, Caroline Tanner, Charles S. Venuto, Karl Kieburtz, Lana M. Chahine, Kathleen L. Poston, Andrew Siderowf, Kenneth Marek, Tanya Simuni, The Parkinson's Progression Markers Initiative   +19 more
wiley   +1 more source

Feasibility and Tolerability of Performing Portable MRI for Neurological Disorders in an Outpatient Neurology Clinic: A Prospective Cohort

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Accessing brain magnetic resonance imaging (MRI) can be challenging, especially for underserved patients, which may lead to disparities in neurological diagnosis. Method This mixed‐methods study enrolled adults with one of four neurological disorders: mild cognitive impairment or dementia of the Alzheimer type, multiple sclerosis ...
Maya L. Mastick, Nomin Enkhtsetseg, Joseph Sadok, Matheus Mochetti, Annabel Sorby Adams, Jennifer Guo, Cristina Trapaga Hacker, Isabella Gomez Hjerthen, Seungwon Lee, Siddharth Satish, Andrew S. Ham, Justin Hill, Denis Balaban, Kevin Kyle, Rebecca L. Gillani, Marcelo Matiello, Aleksandar Videnovic, Eric C. Klawiter, W. Taylor Kimberly, Farrah J. Mateen   +19 more
wiley   +1 more source