Results 41 to 50 of about 22,434 (267)

Equine coronavirus infection and replication in equine intestinal enteroids

Veterinary Research
In this study, equine intestinal enteroids (EIEs) were generated from the duodenum, jejunum, and ileum and inoculated with equine coronavirus (ECoV) to investigate their suitability as in vitro models with which to study ECoV infection ...
Yoshinori Kambayashi, Manabu Nemoto, Akihiro Ochi, Daiki Kishi, Takanori Ueno, Koji Tsujimura, Hiroshi Bannai, Nanako Kawanishi, Minoru Ohta, Tohru Suzuki   +9 more
doaj   +1 more source

Heritability estimates of the position and number of facial hair whorls in Thoroughbred horses

BMC Research Notes, 2019
Objective According to oral traditions of horse caretakers and trainers, the differences in the position and number of facial hair whorls may be associated with temperamental traits.
Tamu Yokomori, Teruaki Tozaki, Hiroshi Mita, Takeshi Miyake, Hironaga Kakoi, Yuki Kobayashi, Kanichi Kusano, Takuya Itou   +7 more
doaj   +1 more source

Increased Risk of Sarcomas in Children With Congenital Anomalies: Findings From the Genetic Overlap Between Anomalies and Cancer in Kids (GOBACK) Registry Linkage Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Pediatric sarcomas are a heterogeneous group of tumors that contribute disproportionately to cancer mortality in children. Although congenital anomalies are among the strongest known risk factors for childhood cancer, the risk of specific sarcoma subtypes among affected individuals has not yet been thoroughly evaluated. Procedure We
Russ Wolters, Ji Yun Tark, Tiffany M. Chambers, Tania A. Desrosiers, Michael E. Scheurer, Charles Shumate, Wendy N. Nembhard, Mahsa M. Yazdy, Eirini Nestoridi, Amanda E. Janitz, Jean Paul Tanner, Russell S. Kirby, Jason L. Salemi, Yao Yu, Chad D. Huff, Sharon E. Plon, Philip J. Lupo, Jeremy M. Schraw   +17 more
wiley   +1 more source

Application of Monte Carlo Methods to Consider Probabilistic Effects in a Race Simulation for Circuit Motorsport

Applied Sciences, 2020
Applying an optimal race strategy is a decisive factor in achieving the best possible result in a motorsport race. This mainly implies timing the pit stops perfectly and choosing the optimal tire compounds.
Alexander Heilmeier, Michael Graf, Johannes Betz, Markus Lienkamp   +3 more
doaj   +1 more source

Used like Pawns or Treated like Kings? How Narratives around Racehorse Welfare in the 2023 Grand National May Affect Public Acceptance: An Informed Commentary

Animals, 2023
The 2023 Grand National steeplechase race was delayed when protesters from the animal rights group, ‘Animal Rising’, gained access to the course just prior to the race. The international media spotlight was focused on what is already a high-profile event
Gemma Pearson, Janet Douglas, Inga Wolframm, Tamzin Furtado   +3 more
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Rational quinidine dosage regimen for atrial fibrillation in Thoroughbred racehorses based on population pharmacokinetics

Frontiers in Veterinary Science
IntroductionQuinidine (QND) sulfate is an effective treatment for atrial fibrillation (AF) in horses, and several dosage regimens have been proposed to address its wide variability in response and potential adverse effects.
Taisuke Kuroda, Yohei Minamijima, Christopher Ken Kinman, Yuji Takahashi, Yusaku Ebisuda, Kaori Inoue, Hiroshi Ishikawa, Hiroshi Mita, Norihisa Tamura, Toshio Nukada, Pierre-Louis Toutain, Pierre-Louis Toutain, Minoru Ohta   +12 more
doaj   +1 more source

The association between Thoroughbred racehorse training practices and musculoskeletal injuries in Victoria, Australia

Frontiers in Veterinary Science, 2023
Catastrophic musculoskeletal injuries (CMI) in horses are associated with both too little and too much high-speed exercise. In order to advise trainers on training and management strategies that minimize the risk of musculoskeletal injury (MSI), a better
Adelene S. M. Wong, Ashleigh V. Morrice-West, Peta L. Hitchens, R. Chris Whitton   +3 more
doaj   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

A Comparison of Devices for Race Day Characterization of North American Turfgrass Thoroughbred Racing Surfaces

Animals, 2023
Both pre-race meet and daily turf surface condition measurements are required by regulations adopted as part of the Horseracing Integrity and Safety Act (HISA). The Orono Biomechanical Surface Tester (OBST) is the primary device used for characterizing a
Peter R. Schmitt, Wayne Sanderson, John (Trey) Rogers, Tyler J. Barzee, Michael (Mick) Peterson   +4 more
doaj   +1 more source