Results 261 to 270 of about 623,879 (355)

A Facile Protocol for C(sp2)–C(sp3) Bond Formation Reactions Toward Functionalized E3 Ligase Ligands

ChemMedChem, EarlyView.
A robust C(sp2)–C(sp3) decarboxylative coupling strategy enables access to new CRBN ligands and degraders with improved physicochemical properties. This synthetic approach is expanding the chemical space beyond C(sp2)–N linkages, fine‐tuning proteolysis‐targeting chimera activities and unlocking previously inaccessible degrader chemotypes.
Anita Maksutova, Thomas M. Geiger, Lorenzo Cianni, Dominika E. Pieńkowska, Jan Gerhartz, Lina Read, Aleša Bricelj, Alexander Herrmann, Maurice Leon Nelles, Yuen Lam Dora Ng, Marcus D. Hartmann, Jan Krönke, Izidor Sosič, Radosław P. Nowak, Michael Gütschow, Christian Steinebach   +15 more
wiley   +1 more source

Anti-Racist Practices in Health Care Organizations-A Qualitative Analysis. [PDF]

Int J Environ Res Public Health
Khan-Gökkaya S, McMillan F, Williams DR.   +2 more
europepmc   +1 more source

Nuestra Comunidad: The Role of Latin American Networks in Supporting Ecologists Throughout Their Careers

The Bulletin of the Ecological Society of America, EarlyView.
Shersingh Joseph Tumber‐Dávila, Angelique Rosa Marín, Rodrigo Felipe Rodrigues do Carmo, Sergio González‐Mollinedo, Luis Y. Santiago‐Rosario, Coral del Mar Valle Rodríguez   +5 more
wiley   +1 more source

A Phase 1, Randomized, Placebo‐Controlled, Multiple‐Dose, Double‐Blind Study to Evaluate and Compare the Pharmacokinetics and Safety of Rimegepant in Healthy Adult Japanese and Caucasian Individuals

Clinical Pharmacology in Drug Development, EarlyView.
Abstract This Phase 1, randomized, placebo‐controlled, double‐blind study assessed the pharmacokinetic profile of rimegepant (25, 75, or 150 mg once daily for 14 days) in healthy Japanese and Caucasian adults. Exposures were modestly increased in Japanese participants compared with Caucasian participants following a single dose of rimegepant (Day 1 ...
Rajinder Bhardwaj, Chay Ngee Lim, Yinhua Li, Kyle T. Matschke, Richard Bertz, Robert Croop, Jing Liu   +6 more
wiley   +1 more source

Confronting Systemic Racism in Occupational Therapy: A Mixed Methods Study

Rachelle Murphy, Karen Park, Christy Billock, Tracy A. Becerra-Culqui, Natalie A Perkins, Rajvinder Bains   +5 more
openalex   +2 more sources

“Train and Hope”: The Role of Restorative Justice Coordinators in Sustaining a Culture of Care in Schools

Conflict Resolution Quarterly, EarlyView.
ABSTRACT This article examines the role of restorative justice coordinators in supporting teachers and schools in adopting a whole‐school approach to restorative justice in education. Coordinators are often tasked with implementing a train‐and‐hope model, in which they receive initial training in restorative justice but are largely left unsupported ...
Crystena Parker‐Shandal, Kristina R. Llewellyn, Sandeep Manku, Mackenzie Leclaire   +3 more
wiley   +1 more source

Weathering the STORM and Forecasting Equity for Older Black Women: Expanding Social Determinants of Health. [PDF]

Int J Environ Res Public Health
Versey HS, Van Vleet S.
europepmc   +1 more source

Navigating the Dual Pandemics: Challenges to Faculty Diversity and Student Success

New Directions for Community Colleges, EarlyView.
Lorenzo Baber, Karla Velasco, Jeongsan Hwang, Gianina Baker   +3 more
wiley   +1 more source