Results 161 to 170 of about 343,927 (326)

Microscopic geared metamachines. [PDF]

open access: yesNat Commun
Wang G   +7 more
europepmc   +1 more source

The slow emergence of the rational investor: Grain markets and grain storage of rural estates in western Germany, eighteenth and early nineteenth centuries

open access: yesThe Economic History Review, EarlyView.
Abstract We develop new datasets of monthly grain prices in 14 urban markets and of the storage and marketing of grain by 5 rural estates located in western Germany between the late seventeenth century and c. 1860. We explore whether observed patterns of monthly prices, sales, and storage of grain are consistent with the rational competitive storage ...
Matthias Hartermann   +2 more
wiley   +1 more source

Questions Should Have Answers

open access: yesEuropean Journal of Philosophy, EarlyView.
ABSTRACT Making sense of the world often requires one to come up with new ideas, including ideas one had previously been unable to think of. How and when should this be done? I propose and defend a norm of rationality linking wondering, belief, and abilities to conceive: one must not both wonder a question and reject all answers to it that one can ...
Michael Deigan
wiley   +1 more source

Negative and zero linear compressibility in copper dicyanamide and tricyanomethanide. [PDF]

open access: yesChem Sci
Chen M   +5 more
europepmc   +1 more source

Dimerization‐dependent NOTCH receptor transactivation unveils a class of highly selective NOTCH signalling inhibitors

open access: yesThe FEBS Journal, EarlyView.
NOTCH signalling is indispensable for tissue homeostasis and, consequently, corruption of its normal function promotes numerous diseases, including cancer. However, the development of targeted therapies has been hampered by inefficacy and overt toxicity. Here, we show that NOTCH receptor dimerization is necessary for receptor transactivation, which has
Xinxin Liu   +9 more
wiley   +1 more source

Oxygen‐independent expression of HIF‐1α during the cell cycle in hepatocellular carcinoma cells controls essential metabolic pathways under normoxia

open access: yesThe FEBS Journal, EarlyView.
In Huh7 cells, HIF‐1α is essential as it maintains the expression of proteins involved in glycolysis and steroid/cholesterol biosynthesis both under normoxia and hypoxia. On the other hand, in HeLa cells, these pathways are induced by HIF‐1α only under hypoxia.
Ioanna‐Maria Gkotinakou   +6 more
wiley   +1 more source

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