Results 51 to 60 of about 722,443 (297)

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Correcting gradient chain induced fat quantification errors in radial multi-echo Dixon imaging using a gradient modulation transfer function

Frontiers in Physics, 2023
Purpose: Multi-echo Stack-of-stars (SoS) radial k-space trajectories with golden angle ordering are becoming popular for free-breathing abdominal Dixon imaging and proton density fat fraction (PDFF) mapping.
Christoph Zöllner, Sophia Kronthaler, Kilian Weiss, Christof Boehm, Jonathan Stelter, Jürgen Rahmer, Peter Börnert, Johannes M. Peeters, Daniela Junker, Dimitrios C. Karampinos   +9 more
doaj   +1 more source

Radial Processes

The Annals of Probability, 1973
Let $X = \{X_t = (X_t^1,\cdots, X_t^d), t \geqq 0\}$ be an isotropic stochastic process with stationary independent increments having its values in $d$-dimensional Euclidean space, $d \geqq 2$. Let $R_t = |X_t|$ be the radial process. It is proved (except for a rather trivial exception) that the Markov process $\{R_t\}$ hits points if and only if the ...
openaire   +2 more sources

Radial trees

Discrete Mathematics, 2009
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Sarada Herke, Christina M. Mynhardt
openaire   +4 more sources

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Enseñanza de la historia del conflicto armado en Colombia: Fundamentos para la construcción de propuestas para su enseñanza en el ámbito universitario. Fundation for teaching the history of armed conflict in university.

Revista Latinoamericana de Estudios Educativos, 2009
En el artículo se aborda un análisis de la historia de Colombia desde la revisión de diversos hechos fundamentales para el desarrollo social, político y económico el país.
Mariela Márquez Quintero
doaj  

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Radial Mandibular Coronoidectomy in a Basset Hound as a Treatment for Temporomandibular Joint Dysplasia

Veterinary Medicine and Science
A ‐year‐old Basset Hound, previously diagnosed with temporomandibular joint dysplasia, presented with a 6‐month history of pain during mastication and frequent open‐mouth locking episodes.
Elena Rappa, Bruno Santos, Marie‐Pauline Maurin   +2 more
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source