Results 51 to 60 of about 1,289,487 (218)

Upadacitinib Restrains the Pathogenic Fitness of CD4+ T Cells and Aberrant B Cell Programming in Optic Neuritis

Advanced Science, EarlyView.
Single‐cell profiling and functional perturbation reveal coordinated JAK1‐pSTAT3 downstream programs in optic neuritis, including MCL1‐dependent fitness of pathogenic CD4+ Tem cells and glycolysis‐linked, cholesterol‐sensitive B‐cell responses associated with RORA. Upadacitinib disrupts this reciprocal T‐B‐cell circuit and alleviates neuroinflammation,
Gengchen Jiang, Qi Jiang, Lian Han, Yue Peng, Xingyu Liu, Tong Yang, Hao Huang, Jiaying Liu, Yuan Gao, Hui Yang, Wenjun Zou, Zhaohuai Li, Wenru Su   +12 more
wiley   +1 more source

SUPERFICIAL RADIAL NEUROPATHY FOLLOWING VENEPUNCTURE

International Journal of Clinical Practice, 2001
SUMMARYA 42‐year‐old female suffered excruciating pain and paraesthesia on venepuncture of the cephalic vein in her left wrist. The left superficial radial nerve was injured. A flexed wrist during venepuncture renders the superficial radial nerve immobile and vulnerable to being punctured by the needle.
J J, Sheu, R Y, Yuan
openaire   +2 more sources

Programmable Self‐Heating Microneedle Patch for on‐Demand Postprandial Glucose Management

Advanced Science, EarlyView.
A programmable self‐heating microneedle patch enables on‐demand, timed‐sequence insulin delivery via user‐triggered quadrant activation. Each activation generates localized heat that melts a phase‐change barrier, accelerating drug release. In diabetic rats, sequential quadrant activation counteracts four meal‐mimicking glucose spikes over 24 h without ...
Yang Zhao, Guifang Pan, Jincai Zhang, Yue Gong, Wenjian Zhang, Huiling Shen, Xingxing Li, Yuehan Ouyang, Hanhan Xie, Jundong Shao   +9 more
wiley   +1 more source

Radial nerve compression following volar plate fixation:

Anales de la Facultad de Medicina
Distal radius fractures are common, especially in the elderly, and typically have excellent outcomes with volar plate fixation. However, complications such as inflammation, tendon rupture, and nerve compression can occur.
Luigi De Bonis Camilotti, Guilherme Machado Fully, Márcio Duarte   +2 more
doaj   +1 more source

Role of SoxE transcription factors in development and disease

Developmental Dynamics, EarlyView.
Abstract Sox8, Sox9, and Sox10 arose by multiple rounds of genome duplications from a single SoxE gene in ancestral vertebrates. In this review, we will briefly discuss the molecular structure and function of SoxE transcription factors and their evolutionary origin. We will then discuss their expression, function, and developmental disorders.
Merin Lawrence, Gerhard Schlosser
wiley   +1 more source

Progressive auditory neuropathy in patients with Leber's hereditary optic neuropathy [PDF]

, 2004
Objective: To investigate auditory neural involvement in patients with Leber's hereditary optic neuropathy (LHON).Methods: Auditory assessment was undertaken in two patients with LHON.
Luxon, LM, Ceranic, B
core  

Bilateral Ophthalmoplegia After Neoadjuvant Pembrolizumab for Oral Cavity Squamous Cell Carcinoma

The Laryngoscope, EarlyView.
The role of immune checkpoint inhibition (ICI) therapy in the treatment of head and neck squamous cell carcinoma (HNSCC) is expanding with increased utilization of neoadjuvant and adjuvant pembrolizumab in the setting of locally advanced disease. This report describes the presentation and management of the first known case of pembrolizumab‐induced ...
Leonard E. Estephan, Peter Jacoby, David M. Cognetti, Steven A. Manobianco   +3 more
wiley   +1 more source

Assessing Radial Nerve Entrapment and Traumatic Radial Neuropathy in the Arm Segment: Clinical Correlations and Electrodiagnostic Findings

Bagcilar Medical Bulletin
Objective: The entrapment of the radial nerve at the spiral groove of the humerus in the arm segment (ERNAS) and traumatic radial neuropathy in the arm segment (TRNAS) are disorders that present with dropped hand.
Şencan Buturak, Halit Fidancı, Halil Can Alaydın, Zülfikar Arlıer   +3 more
doaj   +1 more source

Ultrasonographic evaluation of the median nerve: normal and variant anatomy and appearance

Journal of Ultrasonography, 2021
The median nerve is a mixed sensory and motor nerve that innervates part of the flexor muscles in the anterior compartment of the forearm and muscles in the lateral part of the hand; palmar cutaneous and digital cutaneous nerves branch from the median ...
Nulle Kitija, Jaudzema Aija
doaj   +1 more source

Clinical Features of Wrist Drop Caused by Compressive Radial Neuropathy and Its Anatomical Considerations

Journal of Korean Neurosurgical Society, 2014
Objective Posture-induced radial neuropathy, known as Saturday night palsy, occurs because of compression of the radial nerve. The clinical symptoms of radial neuropathy are similar to stroke or a herniated cervical disk, which makes it difficult to ...
Bo Ram Han, Jun-Cho Yong, Jin Seo Yang, S. Kang, H. Choi   +4 more
semanticscholar   +1 more source