Results 51 to 60 of about 427,255 (213)

High‐Throughput Mechanical Rupture of Nuclear Envelope and the Intracellular Dynamics of Massive Wound Repair

Advanced Science, EarlyView.
A microfluidic device with monolithically integrated nanostructures enables high‐throughput wounding of the cell membrane and nuclear envelope. The spatial distribution of charged multivesicular body protein 4B (CHMP4B) within the cell is mapped before and after wounding, showing involvement in repair of both the cell membrane and nuclear envelope ...
Apresio K. Fajrial, Leyla Akh, Stephanie E. Schneider, Wei Tan, Corey P. Neu, Xiaoyun Ding   +5 more
wiley   +1 more source

Risk of radial nerve injury during deltoid intramuscular injection in shoulder internal rotation and abduction position-cadaveric anatomical study

Human Vaccines & Immunotherapeutics
Radial nerve injury following intramuscular injection into the upper arm is rare but clinically significant. Although injection-site selection is important, the effect of shoulder position, particularly internal rotation, on radial nerve location remains
Naoki Minami, Yasuaki Nakanishi, Shimpei Kurata, Tadanobu Onishi, Shohei Omokawa, Apichat Sinthubua, Pasuk Mahakkanukrauh, Kenji Kawamura   +7 more
doaj   +1 more source

Upadacitinib Restrains the Pathogenic Fitness of CD4+ T Cells and Aberrant B Cell Programming in Optic Neuritis

Advanced Science, EarlyView.
Single‐cell profiling and functional perturbation reveal coordinated JAK1‐pSTAT3 downstream programs in optic neuritis, including MCL1‐dependent fitness of pathogenic CD4+ Tem cells and glycolysis‐linked, cholesterol‐sensitive B‐cell responses associated with RORA. Upadacitinib disrupts this reciprocal T‐B‐cell circuit and alleviates neuroinflammation,
Gengchen Jiang, Qi Jiang, Lian Han, Yue Peng, Xingyu Liu, Tong Yang, Hao Huang, Jiaying Liu, Yuan Gao, Hui Yang, Wenjun Zou, Zhaohuai Li, Wenru Su   +12 more
wiley   +1 more source

Association of the mtDNA m.4171C>A/MT-ND1 mutation with both optic neuropathy and bilateral brainstem lesions [PDF]

, 2014
Background: An increasing number of mitochondrial DNA (mtDNA) mutations, mainly in complex I genes, have been associated with variably overlapping phenotypes of Leber’s hereditary optic neuropathy (LHON), mitochondrial encephalomyopathy with stroke ...
Cristina Scaduto, Tonon C, Caporali L, NASSETTI, STEFANIA-ALESSANDRA, Daniela Brunetto, Nassetti, Stefania, Raffaele Lodi, Tonon, Caterina, Francesco Toni, Stipa C, Carelli V., D. Brunetto, Antonio Torroni, A. Torroni, Caterina Tonon, Leonardo Caporali, F. Gandini, Chiara La Morgia, Toni, Francesco, Toni F, Nassetti S, Lodi R, Brunetto D, Anna Olivieri, Francesca Gandini, La Morgia C, Brunetto, Daniela, Parmeggiani, Antonia, Carlotta Stipa, Gandini, Francesca, Scaduto C, C. Scaduto, Stefania Nassetti, Valerio Carelli, Stipa, Carlotta, Carelli, Valerio, Scaduto, Cristina, Lodi, Raffaele, La Morgia, Chiara, Antonia Parmeggiani, Caporali, Leonardo, Torroni, Antonio, Olivieri, Anna, A. Olivieri, Parmeggiani A   +44 more
core   +2 more sources

Iatrogenic Damage to the Radial Nerve During Osteosynthesis of the Humerus. Prevention, Diagnosis and Treatment

Неотложная медицинская помощь, 2020
THE RELEVANCE is determined by the significant frequency of iatrogenic injuries of the radial nerve during internal osteosynthesis of the humerus, long-lasting functional disorders, a large number of unsatisfactory results, as well as the lack of a ...
Y. A. Bogolyubsky, A. M. Fayn, A. V. Sachkov, I. I. Mazhorova, A. Y. Vaza, R. S. Titov, V. B. Bondarev, A. Y. Sergeyev   +7 more
doaj   +1 more source

Total Elbow Arthroplasty: Tips and Tricks in the Setting of Arthritis and Fracture Care

Arthroscopy Techniques, EarlyView.
Abstract The aim of this article is to illustrate our technique for total elbow arthroplasty, acknowledging the key technological advancements and evidence‐based techniques that have emerged in the last 2 decades. In this technical note, we describe our pearls for a reproducible and reliable total elbow arthroplasty procedure.
Benjamin Kerzner, Kyleen Jan, Alexander L. Hornung, John F. Hoy, Xavier C. Simcock   +4 more
wiley   +1 more source

The Background of Mitochondrial DNA Haplogroup J Increases the Sensitivity of Leber's Hereditary Optic Neuropathy Cells to 2,5-Hexanedione Toxicity [PDF]

, 2009
Leber's hereditary optic neuropathy (LHON) is a maternally inherited blinding disease due to mitochondrial DNA (mtDNA) point mutations in complex I subunit genes, whose incomplete penetrance has been attributed to both genetic and environmental factors ...
Achilli Alessandro, GHELLI, ANNA MARIA, Mattioli Stefano, Pala M., Barbieri, Anna, Vidoni S., Torroni Antonio, Carelli Valerio, Anna Barbieri, Vidoni, Sara, Valerio Carelli, Carelli, Valerio, Ghelli, Anna, Mattioli, Stefano, Torroni, Antonio, Iommarini, Luisa, Zanna, Claudia, Pala, Maria, Vidoni Sara, Stefano Mattioli, Antonio Torroni, Achilli A., ZANNA C, Porcelli Anna Maria, Zanna Claudia, Pala Maria, MATTIOLI S, Luisa Iommarini, GHELLI A, Achilli, Alessandro, IOMMARINI L, Rugolo, Michela, Torroni A., Porcelli, Anna Maria, CARELLI V., Ghelli Anna, Rugolo Michela, BARBIERI A, RUGOLO M, PORCELLI AM, Anna Ghelli, Barbieri Anna, Sara Vidoni, Maria Pala, Alessandro Achilli, Anna Maria Porcelli, Michela Rugolo, Claudia Zanna, Iommarini Luisa, VIDONI S   +49 more
core   +1 more source

A case report of thumb weakness misdiagnosed as radial neuroma and resulting in upper limb dysfunction after surgery

Frontiers in Rehabilitation Sciences
A 37-year-old female patient was misdiagnosed with radial neuroma due to thumb weakness. After surgery, the weakness of her upper limbs worsened over 4 months.
Zhiqi Lin, Zhiqi Lin, Keyun Gan, Keyun Gan, Yuanbin Yang, Longyue Yi, Longyue Yi, Wei Yao, Wei Yao   +8 more
doaj   +1 more source

“Saturday Night Palsy”: Lessons from a Patient

Gazeta Médica, 2023
“Saturday night palsy”, also known as “lovers’ paralysis”, is a neuropathy of the radial nerve, caused by extrinsic compression at a certain point in its path along the humerus, usually at the level of the spiral groove. This designation is based on the
Teresa Sarmento de Beires, Andreia Eiras
doaj  

A panorama of radial nerve pathologies- an imaging diagnosis: a step ahead

Insights into Imaging, 2018
The radial nerve has a long and tortuous course in the upper limb. Injury to the nerve can occur due to a multitude of causes at many potential sites along its course. The most common site of involvement is in the proximal forearm affecting the posterior
Aakanksha Agarwal, Abhishek Chandra, Usha Jaipal, Narender Saini   +3 more
doaj   +1 more source