Results 31 to 40 of about 59,991 (265)

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Simulations for Planning Next-generation Exoplanet Radial Velocity Surveys

open access: yesThe Astronomical Journal, 2023
Future direct imaging missions similar to the HabEx and LUVOIR mission concepts aim to catalog and characterize Earth-mass analogs around nearby stars.
Patrick D Newman   +8 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Design and Commissioning of an Iodine Cell for the ESPRESSO Spectrograph

open access: yesThe Astronomical Journal
High-resolution echelle spectrographs remain the backbone of precision Doppler radial velocity (RV) programs, detecting almost all known exoplanets within 50 pc. Precision Doppler RV spectrographs have traditionally fallen into two camps.
Gillian Nave, R. Paul Butler
doaj   +1 more source

Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley   +1 more source

GAIA SPECTROSCOPY AND RADIAL VELOCITIES [PDF]

open access: yesEAS Publications Series, 2002
proceedings of Les Houches 2001 summer school "GAIA, an European Space Project", published by Editions De Physique, 14 ...
openaire   +2 more sources

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

open access: yesFEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty   +13 more
wiley   +1 more source

VARIATIONS OF THE β CEPHEI Hα LINE PARAMETERS IN 1993 - 1998.

open access: yesOdessa Astronomical Publications, 2017
We use high-dispersion CCD spectrograms obtained in 1993 - 1998 to study parameter variations of the absorption and emission components Hα line of the star β Cephei. We show that radial velocity of the emission component does not depend on star pulsation
E. A. Panko, A. E. Tarasov
doaj   +1 more source

The Radial Velocities of Globular Clusters [PDF]

open access: yesProceedings of the National Academy of Sciences, 1930
The following discussion of the radial velocities of globular clusters originated in conversations which I had with Dr. Zwicky of the California Institute of Technology during my stay at the Mount Wilson Observatory. Since it depends essentially on the validity of Stromberg's solution for the motion of the sun relative to the system of the globular ...
openaire   +2 more sources

Commission 30: Radial Velocities: (Vitesses Radiales) [PDF]

open access: yesTransactions of the International Astronomical Union, 2000
Commission 30 has 120 members in 28 countries who are active in the area of radial velocities. During the past triennium 11 new members have joined the commission. The work of the commission covers a wide range of topics all of which concern the application of the Doppler effect to astronomical objects, including galaxies and the interstellar medium as
J.B. Hearnshaw   +9 more
openaire   +2 more sources

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