Results 81 to 90 of about 19,245 (261)
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
BuildingsThis study aims to develop and evaluate a vertically rotated fin shading system for an energy-efficient, user-friendly office space. The system was designed to protect a 4 × 8 m office room with a south-facing facade from excessive solar radiation and ...
Marcin Brzezicki
doaj +1 more source
Remote Sensing, 2019 Midwave infrared (MWIR) band of 3.75 μm is important in satellite remote sensing in many applications. This band observes daytime reflectance and nighttime radiance according to the Earth’s and the Sun’s effects.
Yerin Kim, Sungwook Hong
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Bird strandings and bright lights at coastal and offshore industrial sites in Atlantic Canada
Avian Conservation and Ecology, 2021 Artificial lights can disorient birds and lead to injury or death. In Atlantic Canada, lights attract birds at sites along the coastline and offshore, but the relative impacts of lights on birds in this region are largely unknown.
Carina Gjerdrum +3 more
doaj
Multispectral Sensor Calibration and Characterization for sUAS Remote Sensing
Sensors, 2019 This paper focuses on the calibration of multispectral sensors typically used for remote sensing. These systems are often provided with "factory" radiometric calibration and vignette correction parameters.
Baabak Mamaghani, Carl Salvaggio
doaj +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source