Results 81 to 90 of about 33,254 (214)

Deep Learning-Generated Nighttime Reflectance and Daytime Radiance of the Midwave Infrared Band of a Geostationary Satellite

open access: yesRemote Sensing, 2019
Midwave infrared (MWIR) band of 3.75 μm is important in satellite remote sensing in many applications. This band observes daytime reflectance and nighttime radiance according to the Earth’s and the Sun’s effects.
Yerin Kim, Sungwook Hong
doaj   +1 more source

Upward radiance radiance during Maria S. Merian cruise MSM21/3 (ARCHEMHAB)

open access: yes, 2013
Upward radiance radiance during Maria S.
Henkel, Rohan   +13 more
core   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

Daylight Comfort Performance of a Vertical Fin Shading System: Annual Simulation and Experimental Testing of a Prototype

open access: yesBuildings
This study aims to develop and evaluate a vertically rotated fin shading system for an energy-efficient, user-friendly office space. The system was designed to protect a 4 × 8 m office room with a south-facing facade from excessive solar radiation and ...
Marcin Brzezicki
doaj   +1 more source

Bird strandings and bright lights at coastal and offshore industrial sites in Atlantic Canada

open access: yesAvian Conservation and Ecology, 2021
Artificial lights can disorient birds and lead to injury or death. In Atlantic Canada, lights attract birds at sites along the coastline and offshore, but the relative impacts of lights on birds in this region are largely unknown.
Carina Gjerdrum   +3 more
doaj  

Multispectral Sensor Calibration and Characterization for sUAS Remote Sensing

open access: yesSensors, 2019
This paper focuses on the calibration of multispectral sensors typically used for remote sensing. These systems are often provided with "factory" radiometric calibration and vignette correction parameters.
Baabak Mamaghani, Carl Salvaggio
doaj   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

open access: yesMolecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

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