Results 41 to 50 of about 19,210 (261)
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
This music score was submitted for the Kaleidoscope 2020 Call for Scores, an open access collaboration with the UCLA Music Library.
openaire +3 more sources
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
The Clouds and the Earth’s Radiant Energy System (CERES) project provides observations of Earth’s radiation budget using measurements from CERES instruments onboard the Terra, Aqua and Suomi National Polar-orbiting Partnership (S-NPP) satellites.
Norman G. Loeb +4 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Improvement of Optical Performances Using the Hybrid CPV
Hybrid Concentrated Photovoltaics (HCPVs) are systems in which additional low-cost silicone solar cells are added to take advantage of the power generated by the diffuse radiation lost when using only multi-junction cells that work only with direct ...
Sarah El Himer, Ali Ahaitouf
doaj +1 more source
In remote sensing, the conversion of at-sensor radiance to surface reflectance for each pixel in a scene is an essential component of many analysis tasks.
Luke J. R. DeCoffe +5 more
doaj +1 more source
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Infrared Multispectral Radiation Temperature Measurement Based on PCA-ELM
In the case of unknown target emissivity, an infrared multispectral radiation temperature measurement method based on principal component analysis (PCA) and extreme learning machine (ELM) is established.
XI Jianhui, JIANG Han, CHEN Bo, FU Li
doaj +1 more source

