Results 51 to 60 of about 2,393,948 (334)

Role of Ionizing Radiation in Neurodegenerative Diseases

Frontiers in Aging Neuroscience, 2018
Ionizing radiation (IR) from terrestrial sources is continually an unprotected peril to human beings. However, the medical radiation and global radiation background are main contributors to human exposure and causes of radiation sickness.
N. Sharma, Rupali Sharma, Deepali Mathur, S. Sharad, Gillipsie Minhas, Kulsajan Bhatia, A. Anand, Sanchita P. Ghosh   +7 more
semanticscholar   +1 more source

Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes

FEBS Letters, EarlyView.
Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley   +1 more source

Public Awareness of Medical Imaging as a Source of Ionizing Radiation Exposure [PDF]

, 2017
Background. Biological effects of exposure to ionizing radiation (IR) are well known. Literature suggests most patients and physicians lack proficient understanding of risks associated with ionizing radiation.
Carney, Jan, Fields, Tim, Hall, Michael J, Hoffman-Contois, Razelle, Irwin, William, Janardhan, Arjun, Leung, Lawrence J, Magier, Samantha, Robbins, Allison B, Warther, Katie C   +9 more
core   +1 more source

Spatial methods for event reconstruction in CLEAN

, 2003
In CLEAN (Cryogenic Low Energy Astrophysics with Noble gases), a proposed neutrino and dark matter detector, background discrimination is possible if one can determine the location of an ionizing radiation event with high accuracy.
Bard, Beacom, Bruyant, Daniel N. McKinsey, Fukuda, Fukuda, Gao, Gay, Horowitz, Kahaner, Kevin J. Coakley, Krol, Lehmann, McKinsey, Nelson, Peplow, Shepp, Vardi, Wood, Yang   +19 more
core   +2 more sources

Cellular Pathways in Response to Ionizing Radiation and Their Targetability for Tumor Radiosensitization

International Journal of Molecular Sciences, 2016
During the last few decades, improvements in the planning and application of radiotherapy in combination with surgery and chemotherapy resulted in increased survival rates of tumor patients. However, the success of radiotherapy is impaired by two reasons:
P. Maier, Linda Hartmann, F. Wenz, C. Herskind   +3 more
semanticscholar   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

Hazards to space workers from ionizing radiation [PDF]

, 1980
A compilation of background information and a preliminary assessment of the potential risks to workers from the ionizing radiation encountered in space is provided.
Lyman, J. T.
core   +1 more source

Ionizing Radiation-Induced Immune and Inflammatory Reactions in the Brain

Frontiers in Immunology, 2017
Radiation-induced late brain injury consisting of vascular abnormalities, demyelination, white matter necrosis, and cognitive impairment has been described in patients subjected to cranial radiotherapy for brain tumors.
K. Lumniczky, T. Szatmári, G. Sáfrány
semanticscholar   +1 more source

TRPM8 levels determine tumor vulnerability to channel agonists

Molecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo, Francesco Giuseppe Carbone, Kristi Buzo, Nicole Annesi, Sacha Genovesi, Annalisa Lorenzato, Karen Widmann, Michela Libergoli, Elisa Marmocchi, Giovanni Bertalot, Alberto Brolese, Mauro Giulio Papotti, Luca Molinaro, Orazio Caffo, Mattia Barbareschi, Alberto Bardelli, Alessandro Romanel, Sabrina Arena, Andrea Lunardi   +18 more
wiley   +1 more source

Implications of the COVID-19 pandemic on self-reported health status and noise annoyance in rural and non-rural Canada

Scientific Reports, 2022
The Canadian Perspectives on Environmental Noise Survey (CPENS), conducted between April 12th, 2021 and May 25th, 2021 coincided with the third wave of the COVID-19 pandemic. Canadians 18 years of age and older (n = 6647) reported the degree to which the
David S. Michaud, Leonora Marro, Allison Denning, Shelley Shackleton, Nicolas Toutant, Emily Cameron-Blake, James P. McNamee   +6 more
doaj   +1 more source