Results 111 to 120 of about 3,531,640 (340)

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

open access: yesMolecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser   +11 more
wiley   +1 more source

Isotropic Radiators [PDF]

open access: yesarXiv, 2003
We give two examples of antennas with isotropic radiation patterns. Because these involve elliptically polarized radiation, they evade the "hairy-ball theorem" that suggests isotropic radiation would be impossible.
arxiv  

Radiative transfer in ultra-relativistic outflows [PDF]

open access: yes, 2010
Analytical and numerical solutions are obtained for the equation of radiative transfer in ultra-relativistic opaque jets. The solution describes the initial trapping of radiation, its adiabatic cooling, and the transition to transparency. Two opposite regimes are examined: (1) Matter-dominated outflow.
arxiv   +1 more source

Late side effects of radiation treatment for head and neck cancer

open access: yesRadiation Oncology Journal, 2020
Patients undergoing radiation therapy for head and neck cancer (HNC) experience significant early and long-term side effects. The likelihood and severity of complications depends on a number of factors, including the total dose of radiation delivered ...
I. Brook
semanticscholar   +1 more source

Germline variants in CDKN2A wild‐type melanoma prone families

open access: yesMolecular Oncology, EarlyView.
Among melanoma‐prone families, wild‐type for CDKN2A and CDK4, some have pathogenic variants in genes not usually linked to melanoma. Furthermore, rare XP‐related variants and variants in MC1R are enriched in such families. Germline pathogenic variants in CDKN2A are well established as an underlying cause of familial malignant melanoma. While pathogenic
Gjertrud T. Iversen   +5 more
wiley   +1 more source

Heart Sparing Radiotherapy Techniques in Breast Cancer: A Focus on Deep Inspiration Breath Hold

open access: yesBreast Cancer: Targets and Therapy, 2022
Hayley B Stowe,1 Neal D Andruska,1 Francisco Reynoso,1 Maria Thomas,1 Carmen Bergom1– 3 1Department of Radiation Oncology, Washington University School of Medicine in St. Louis, St.
Stowe HB   +4 more
doaj  

Radiation-induced lung toxicity – cellular and molecular mechanisms of pathogenesis, management, and literature review

open access: yesRadiation Oncology, 2020
Lung, breast, and esophageal cancer represent three common malignancies with high incidence and mortality worldwide. The management of these tumors critically relies on radiotherapy as a major part of multi-modality care, and treatment-related toxicities,
L. Käsmann   +10 more
semanticscholar   +1 more source

Understanding and measuring mechanical signals in the tumor stroma

open access: yesFEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz   +3 more
wiley   +1 more source

Intraoperative radiation therapy for breast cancer patients: current perspectives

open access: yesBreast Cancer: Targets and Therapy, 2017
Sunil W Dutta,1 Shayna L Showalter,2 Timothy N Showalter,1 Bruce Libby,1 Daniel M Trifiletti1 1Department of Radiation Oncology, 2Division of Surgical Oncology, Department of Surgery, University of Virginia School of Medicine, Charlottesville, VA, USA ...
Dutta SW   +4 more
doaj  

Characterisation of the role played by ELMO1, GPR141 and the intergenic polymorphism rs918980 in Fuchs' dystrophy in the Indian population

open access: yesFEBS Open Bio, EarlyView.
This study reports the upregulation of ELMO1 and GPR141 in human Fuchs' endothelial corneal dystrophy (FECD) corneal endothelium and ultraviolet A‐induced FECD mice model. A genetic association of an intergenic single nucleotide polymorphism rs918980 present between both genes is observed with FECD in the Indian population.
Susmita Sharma   +3 more
wiley   +1 more source

Home - About - Disclaimer - Privacy