Results 261 to 270 of about 2,377,244 (375)

Reengineering Endogenous Targeting Lipid Nanoparticles (ENDO) for Systemic Delivery of mRNA to Pancreas

open access: yesAdvanced Materials, EarlyView.
ENDO lipid nanoparticles containing cholecalciferol as a fifth component demonstrate mRNA delivery to the pancreas with 99% selectivity, including beta cells. This platform shows minimal toxicity and sustained protein expression for up to 3 days in a dose‐dependent manner, offering a novel approach to pancreas‐specific mRNA delivery and gene therapy ...
Ivan Isaac   +7 more
wiley   +1 more source

Ultrathin Mesoporous Metal‐Organic Framework Nanosheets

open access: yesAdvanced Materials, EarlyView.
A bottom‐up interface‐directed co‐assembly strategy enables the synthesis of ultrathin 2D mesoporous UiO‐66(Ce) nanosheets with tunable thickness and uniform mesopores. The enhanced mass transport and accessible active sites significantly improve performance, highlighting the synergistic effects of 2D morphology and mesopores in metal‐organic ...
Yingji Zhao   +12 more
wiley   +1 more source

Modulating Single‐Atom Pt Coordination for Enhanced Low‐Temperature Ammonia Fuel Cell Electrocatalysis

open access: yesAdvanced Materials, EarlyView.
A bifunctional Pt single‐atom catalyst (Pt‐DG‐1) is discovered with enhanced ammonia oxidation reaction and oxygen reduction reaction mass activities compared to commercial Pt/C. It is shown that modulating the coordination environment of Pt single atoms is crucial towards dictating the electrocatalytic activity.
Tong Wu   +10 more
wiley   +1 more source

Elastic Energy Storage in Biological Materials: Internal Stresses and Their Functionality

open access: yesAdvanced Materials, EarlyView.
Harnessing and storing internally generated elastic energy is a clever strategy by biological materials to perform functions like shape transformation, movement, and predation. This review explores how biological systems manipulate mechanisms like atomic or protein integration into minerals, protein conformational shifts, phase transitions, and osmotic
Shahrouz Amini   +3 more
wiley   +1 more source

Playing Hard with Si: Challenges and Opportunities for New Materials in Radiation Therapy Dosimetry

open access: yesAdvanced Materials, EarlyView.
Silicon has been a cornerstone material of radiation therapy dosimetry for many decades, providing somewhat unchallenged performance. However, there are caveats to its use, requiring complex designs and, often, correction factors to provide accurate measurements.
James Cayley   +9 more
wiley   +1 more source

Enhancing X‐Ray Detection Sensitivity Through Hybrid Active Layers of PBDB‐T:ITIC and CdSe Core 2D Nanoplatelets

open access: yesAdvanced Materials Interfaces, EarlyView.
A hybrid semiconductor is fabricated by directly synthesizing 5ML CdSe Core into two organic semiconductors PBDB‐T:ITIC (see). The fabricated hybrid device is systematically analyzed for parameter values such as PCE, Jsc, Rs, and mobility, and corresponding TEM, AFM, XRD, etc. images are included.
Jaewon Son   +3 more
wiley   +1 more source

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