Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Update on Radiation Dose From Galactic and Solar Protons at the Moon Using the LRO/CRaTER Microdosimeter [PDF]
, 2015 The NASA Lunar Reconnaissance Orbiter (LRO) has been exploring the lunar surface and radiation environment since June 2009. In Mazur et al. [2011] we discussed the first 6 months of mission data from a microdosimeter that is housed within the Cosmic Ray ...
Blake, J. B. +6 more
core +2 more sources
Radiation dose Estimation: An in vitro Measurement for Isparta-Turkey
, 2015 People have always been exposed to radiation and it is important to determine this radiation dose for radioactive contamination. The main source for this radiation is from earth and is can change with the geological structure.
I. Akkurt, N. Uyanık, K. Günoğlu
semanticscholar +1 more source
Low-Dose CT Image Denoising Using a Generative Adversarial Network With Wasserstein Distance and Perceptual Loss [PDF]
IEEE Transactions on Medical Imaging, 2017 The continuous development and extensive use of computed tomography (CT) in medical practice has raised a public concern over the associated radiation dose to the patient.
Qingsong Yang +9 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Optimization and audit of radiation dose during percutaneous transluminal coronary angioplasty
Journal of Medical Physics, 2007 The percutaneous transluminal coronary angioplasty (PTCA) is one of the interventional procedures which impart high radiation doses to patients compared to the other cardiologic procedures. This study intends to audit and optimize radiation dose imparted
Livingstone Roshan +4 more
doaj
Advanced dosimetry systems for the space transport and space station [PDF]
, 1972 Advanced dosimetry system concepts are described that will provide automated and instantaneous measurement of dose and particle spectra. Systems are proposed for measuring dose rate from cosmic radiation background to greater than 3600 rads/hr.
Clark, B. C. +2 more
core +1 more source
2D mapping of radiation dose and clonogenic survival for accurate assessment of in vitro X-ray GRID irradiation effects [PDF]
, 2022 Delmon Arous +5 more
openalex +1 more source
Targeting p38α in cancer: challenges, opportunities, and emerging strategies
Molecular Oncology, EarlyView.p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley +1 more source