Results 51 to 60 of about 2,553,170 (258)

Enhancement of bio-protective functions by low dose/dose-rate radiation [PDF]

, 2006
Effects of low-dose-rate gamma-irradiation on the process of tumorigenesis were investigated in mice treated with a carcinogenic agent or irradiated with high dose X-rays at a high dose rate.
Nomura, Takaharu, Sakai, Kazuo, Ina, Yasihiro   +2 more
core   +3 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Patient doses in ct, dental cone beam ct and projection radiography in Finland, with emphasis on paediatric patients [PDF]

, 2008
Diagnostic radiology represents the largest man-made contribution to population radiation doses in Europe. To be able to keep the diagnostic benefit versus radiation risk ratio as high as possible, it is important to understand the quantitative ...
Kiljunen, Timo
core  

Reevaluating the Paradox: Does Low-Dose Radiation from A-Bombs Affect Lifespan and Cancer Mortality? [PDF]

Journal of Biomedical Physics and Engineering
Reevaluating the Paradox: Does Low-Dose Radiation from A-Bombs Affect Lifespan and Cancer Mortality?Reevaluating the Paradox: Does Low-Dose Radiation from A-Bombs Affect Lifespan and Cancer Mortality?Reevaluating the Paradox: Does Low-Dose Radiation from
Razieh Rashidfar, Zeynab Seyedi Sarhad, Seyed Mohammad Javad Mortazavi, Lembit Sihver   +3 more
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Coupled experiment/simulation approach for the design of radiation-hardened rare-earth doped optical fibers and amplifiers [PDF]

, 2011
We developed an approach to design radiation-hardened rare earth -doped fibers and amplifiers. This methodology combines testing experiments on these devices with particle swarm optimization (PSO) calculations.
F. Prudenzano, Mescia, L, Vivona, M., Girard, S, Boukenter, Aziz, A. Boukenter, Goiffon, V, Cannas, M., V. Goiffon, Mescia, Luciano, Boukenter, A, L. Mescia, Vivona, Marilena, Mescia, L., R. Boscaino, Cadier, B., P. Paillet, Paillet, P., Y. Ouerdane, Boukenter, A., Paillet, P, Paillet, Philippe, Marcandella, C, Cadier, Benoît, S. Girard, A. Laurent, Laurent, A, Robin, T, C. Marcandella, Goiffon, Vincent, Cadier, B, Ouerdane, Y., Ouerdane, Y, Girard, Sylvain, Prudenzano F, Robin, Thierry, F. Robin, Prudenzano, F, Laurent, Arnaud, Boscaino, Roberto, T. Robin, Robin, T., B. Cadier, Marcandella, C., Goiffon, V., Cannas, Marco, M. Cannas, Prudenzano, F., Boscaino, R., Prudenzano, Francesco, Ouerdane, Youcef, M. Vivona, Girard, Sébastien, Marcandella, Claude, Laurent, A.   +54 more
core   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

A new mathematical model for radiation cell killing mechanism: Target cumulating model [PDF]

, 2009
There are numerous mathematical or statistical models have been given out for radiation cell killing mechanism. Unfortunately, none of the model could explain the mechanism perfectly.
Xie Congyin, Zhang Li, Zhao Liang, Wu Shixiu   +3 more
core  

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

Low-dose radiation research insights in experimental animals: A gateway to therapeutic implications [PDF]

Veterinary World
In recent years, a significant research effort has been underway to explore the effects of low-dose radiation (LDR). Animal models play a key role in various fields of research, including biomedicine, pharmaceutical, environmental, and behavioral studies.
Nayanatara Arunkumar, Megha Gokul, Harini Narayanam, A. K. Ananya   +3 more
doaj   +1 more source