Results 1 to 10 of about 10,823,759 (306)

Prevalence of tanning equipment use among Canadians

Preventive Medicine Reports, 2021
The objective of this study was to collect prevalence estimates of indoor tanning usage and associated injuries in Canada. The rapid response component of the 2019 Canadian Community Health Survey collected data on the use of tanning equipment in the ...
Sami S. Qutob, James P. McNamee, Orly Brion   +2 more
doaj   +1 more source

Deep learning for incidence rate prediction and radiation risk assessment of solid tumors

Scientific Reports
Accurately estimating radiation risk is crucial for protecting public health, establishing safety standards, and advancing research in radiation safety.
Zhenqiu Liu, Tomoki Nakamizo, Munechika Misumi, Satoru Ono, Igor Shuryak, Robert L. Ullrich   +5 more
doaj   +1 more source

Epidemiological study of health effects in Fukushima Emergency Workers: Progress report on the Health Examination Study, 2016-2019

Environmental Advances, 2022
To clarify the long-term health effects from radiation exposure in emergency workers who responded to the radiation accident at the Fukushima Daiichi Nuclear Power Plant of Tokyo Electric Power Company, which was hit by a tsunami caused by the 2011 off ...
Hiroko Kitamura, Waka Ohishi, Kazunori Kodama, Toshiteru Ohkubo   +3 more
doaj   +1 more source

Mutational Signatures in Radiation-Induced Cancer: A Review of Experimental Animal and Human Studies

Biology
Ionizing radiation can damage DNA, leading to mutations, and is a risk factor for cancer. Based on the assumption that all radiation exposure poses a risk in linear proportion to its dose, ionizing radiation is considered a non-threshold carcinogen ...
Kazuhiro Daino, Chizuru Tsuruoka, Atsuko Ishikawa, Shizuko Kakinuma, Tatsuhiko Imaoka   +4 more
doaj   +1 more source

Mutational profiles of spontaneous and radiation-related mammary carcinomas in a rat model of Brca1 haploinsufficiency

Scientific Reports
Female carriers of a heterozygous germline mutation in BRCA1/2 have a high risk of breast cancer. Although recent research has suggested that genomic instability via BRCA1/2 haploinsufficiency contributes to the early phase of BRCA-associated ...
Yuzuki Nakamura, Kazuhiro Daino, Atsuko Ishikawa, Shizuko Kakinuma, Yukiko Nishimura-Yano, Kento Nagata, Masaru Takabatake, Mayumi Nishimura, Tomoji Mashimo, Kazumasa Inoue, Tatsuhiko Imaoka   +10 more
doaj   +1 more source

Germline DNA Retention in Murine and Human Rearranged T Cell Receptor Gene Coding Joints: Alternative Recombination Signal Sequences and V(D)J Recombinase Errors

Frontiers in Immunology, 2019
The genes coding for the antigenic T cell receptor (TR) subunits are assembled in thymocytes from discrete V, D, and J genes by a site-specific recombination process.
Justyna Mika, Sylwia Kabacik, Christophe Badie, Joanna Polanska, Serge M. Candéias   +4 more
doaj   +1 more source

Hedgehog/GLI Signaling at the Interface of Sterol Metabolism, Mitochondrial ROS Signaling and Cellular Plasticity

Antioxidants
Classically, Hedgehog (Hh)/GLI signaling is recognized as a developmental pathway. Increasing evidence indicates that it also contributes to cellular metabolism and adaptation to stress.
Nicolas Jullien, Sabine François
doaj   +1 more source

In vitro study of radiosensitivity in colorectal cancer cell lines associated with Lynch syndrome

Frontiers in Public Health
IntroductionLynch syndrome patients have an inherited predisposition to cancer due to a deficiency in DNA mismatch repair (MMR) genes which could lead to a higher risk of developing cancer if exposed to ionizing radiation. This pilot study aims to reveal
Mingzhu Sun, Jayne Moquet, Stephen Barnard, Hannah Mancey, David Burling, Rachel Baldwin-Cleland, Kevin Monahan, Andrew Latchford, David Lloyd, Simon Bouffler, Christophe Badie, Nicola A. Anyamene, Elizabeth Ainsbury, Elizabeth Ainsbury   +13 more
doaj   +1 more source

Potential benefits of cool roofs in reducing heat-related mortality during heatwaves in a European city

Environment International, 2019
Hot weather can exacerbate health conditions such as cardiovascular and respiratory diseases, and lead to heat stroke and death. In built up areas, temperatures are commonly observed to be higher than those in surrounding rural areas, due to the Urban ...
H.L. Macintyre, C. Heaviside
doaj   +1 more source

Colorectal cancers associated with mismatch repair deficiency

Frontiers in Medicine
This review aims to summarize the latest updates in the prevention, diagnosis, treatment and management of colorectal cancers (CRCs) associated with mutation(s) or alteration(s) in the DNA mismatch repair (MMR) genes.
Mingzhu Sun, Kevin Monahan, Kevin Monahan, Jayne Moquet, Stephen Barnard   +4 more
doaj   +1 more source