Results 41 to 50 of about 3,146,049 (300)

Retrospective Analysis of Donor Lymphocyte Infusions in Pediatric Patients With Mixed Chimerism After Hematopoietic Stem Cell Transplantation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Allogeneic hematopoietic stem cell transplantation (alloHSCT) is an essential therapy for several malignant and nonmalignant diseases, but relapse and graft loss remain the principal threats to its success. Routine monitoring of chimerism and minimal residual disease (MRD) enables early detection of imminent recurrence and guides ...
Carmen Junk, Sebastian Michaelis, Michaela Döring, Thomas Eichholz, Ursula Holzer, Martin Ebinger, Tim Flaadt, Rupert Handgretinger, Peter Lang, Jan Frederic Weller, Markus Mezger   +10 more
wiley   +1 more source

Correction: Park et al. ABCA1-Mediated EMT Promotes Papillary Thyroid Cancer Malignancy through the ERK/Fra-1/ZEB1 Pathway. Cells 2023, 12, 274

Cells
Error in Figure [...]
Ji-Hye Park, Jae-Kyung Myung, Sun-Joo Lee, Hyewon Kim, Soyeon Kim, Seung-Bum Lee, Hyosun Jang, Won-Il Jang, Sunhoo Park, Hyunwon Yang, Sehwan Shim, Min-Jung Kim   +11 more
doaj   +1 more source

Quantitative Assessment of Human Exposure - UVA Radiation

, 2005
Humans are exposed to ultraviolet radiation in their normal day-to-day lives. Much research has been conducted into the impact of exposure to UVB radiation (280 – 320nm), whist research into impact of exposures to UVA radiation (320 – 400 nm) is gaining ...
Macaranas, J. M., Kimlin, Michael, Macaranas, Julie, Parisi, A. V., Turnbull, D. J., Parisi, Alfio, Turnbull, David, Kimlin, M. G.   +7 more
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Thyroid cancer after childhood exposure to external radiation : An updated pooled analysis of 12 studies

, 2016
Studies have causally linked external thyroid radiation exposure in childhood with thyroid cancer. In 1995, investigators conducted relative risk analyses of pooled data from seven epidemiologic studies. Doses were mostly 50 Gy.
Shore, Roy, Damber, Lena,, Pottern, Linda,, Holmberg, Erik, Anderson, Harald, Sakata, Ritsu,, Bhatti, Parveen,, Adams, M. Jacob, Veiga, Lene H. S., Lubin, Jay H., Anderson, Harald,, Inskip, Peter, Adams, M. Jacob,, Kleinerman, Ruth,, Tucker, Margaret, Lundell, Marie, Pottern, Linda, Holmberg, Erik,, Sadetzki, Siegal, Neta, Gila,, Lundell, Marie,, Tucker, Margaret,, Sadetzki, Siegal,, De Vathaire, Florent,, Schneider, Arthur B.,, Johansson, Robert, Johansson, Robert,, De Vathaire, Florent, Neta, Gila, Sakata, Ritsu, Hawkins, Michael M.,, Shore, Roy,, Schneider, Arthur B., Veiga, Lene H S, Damber, Lena, Bhatti, Parveen, Veiga, Lene H S,, Inskip, Peter,, Lund University., Lubin, Jay H.,, Hawkins, Michael M., Kleinerman, Ruth   +41 more
core   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Reduction of radiation exposure to operating physician and assistant using a real-time auditory feedback dosimeter during femoral artery puncturing: a study on swine model

European Radiology Experimental, 2019
Background Real-time dosimeters may create a relatively safer environment not only for the patient but also for the physician and the assistant as well. We propose the use of a real-time radiation measurement dosimeter having auditory feedback to reduce ...
Muhammad Umair Ahmad Khan, Byung-Ju Yi
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source