Results 61 to 70 of about 2,199,437 (323)

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Development of radiation hard scintillators [PDF]

Radiation Physics and Chemistry, 1993
The authors have demonstrated that the radiation stability of scintillators made from styrene polymer is very much improved by compounding with pentaphenyltrimethyltrisiloxane (DC 705 vacuum pump oil). The resulting scintillators are softer than desired, so they decided to make the scintillators directly from monomer where the base resin could be ...
Markley, F., Davidson, M., Keller, J., Foster, G., Pla-Dalmau, A., Harmon, J., Biagtan, E., Schueneman, G., Senchishin, V., Gustfason, H., Rivard, M.   +10 more
openaire   +5 more sources

SiCILIA—Silicon Carbide Detectors for Intense Luminosity Investigations and Applications

Sensors, 2018
Silicon carbide (SiC) is a compound semiconductor, which is considered as a possible alternative to silicon for particles and photons detection.
Salvatore Tudisco, Francesco La Via, Clementina Agodi, Carmen Altana, Giacomo Borghi, Maurizio Boscardin, Giancarlo Bussolino, Lucia Calcagno, Massimo Camarda, Francesco Cappuzzello, Diana Carbone, Salvatore Cascino, Giovanni Casini, Manuela Cavallaro, Caterina Ciampi, Giuseppe Cirrone, Giacomo Cuttone, Alberto Fazzi, Dario Giove, Giuseppe Gorini, Luca Labate, Gaetano Lanzalone, Grazia Litrico, Giuseppe Longo, Domenico Lo Presti, Marco Mauceri, Roberto Modica, Maurizio Moschetti, Annamaria Muoio, Franco Musumeci, Gabriele Pasquali, Giada Petringa, Nicolò Piluso, Giacomo Poggi, Stefania Privitera, Sebastiana Puglia, Valeria Puglisi, Marica Rebai, Sabina Ronchin, Antonello Santangelo, Andrea Stefanini, Antonio Trifirò, Massimo Zimbone   +42 more
doaj   +1 more source

Characterisation of AMS H35 HV-CMOS monolithic active pixel sensor prototypes for HEP applications

, 2018
Monolithic active pixel sensors produced in High Voltage CMOS (HV-CMOS) technology are being considered for High Energy Physics applications due to the ease of production and the reduced costs.
Benoit, M., Casanova, R., Cavallaro, E., Di Bello, F. A., Figueras, E. Vilella, Förster, F., Grinstein, S., Iacobucci, G., Perić, I., Pinto, M. Vicente Barrero, Puigdengoles, C., Terzo, S.   +11 more
core   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Precision Crystal Calorimeters in High Energy Physics: Past, Present and Future [PDF]

, 2006
Precision crystal calorimeters traditionally play an important role in high energy physics experiments. In the last two decades, it faces a challenge to maintain its precision in a hostile radiation environment.
Zhu, Ren-Yuan
core   +1 more source

Radiation hardness of a p-channel notch CCD developed for the X-ray CCD camera onboard the XRISM satellite [PDF]

Journal of Instrumentation, 2019
We report the radiation hardness of a p-channel CCD developed for the X-ray CCD camera onboard the XRISM satellite. This CCD has basically the same characteristics as the one used in the previous Hitomi satellite, but newly employs a notch structure of ...
Y. Kanemaru, J. Sato, K. Mori, H. Nakajima, Y. Nishioka, A. Takeda, K. Hayashida, H. Matsumoto, J. Iwagaki, K. Okazaki, K. Asakura, T. Yoneyama, H. Uchida, H. Okon, T. Tanaka, T. Tsuru, H. Tomida, T. Shimoi, T. Kohmura, K. Hagino, H. Murakami, S. Kobayashi, M. Yamauchi, I. Hatsukade, M. Nobukawa, K. Nobukawa, J. Hiraga, H. Uchiyama, K. Yamaoka, M. Ozaki, T. Dotani, H. Tsunemi, T. Hamano   +32 more
semanticscholar   +1 more source

HV/HR-CMOS sensors for the ATLAS upgrade—concepts and test chip results [PDF]

, 2015
In order to extend its discovery potential, the Large Hadron Collider (LHC) will have a major upgrade (Phase II Upgrade) scheduled for 2022. The LHC after the upgrade, called High-Luminosity LHC (HL-LHC), will operate at a nominal leveled instantaneous ...
Backhaus, M., Barbero, M., Bates, R., Blue, A., Bompard, F., Breugnon, P., Buttar, C., Capeans, M., Clemens, J. C., Feigl, S., Ferrere, D., Fougeron, D., Garcia-Sciveres, M., George, M., Godiot-Basolo, S., Gonella, L., Gonzalez-Sevilla, S., Große-Knetter, J., Hemperek, T., HV CMOS Collaboration, Hynds, D., Hügging, F., Iacobucci, G., Kreidl, C., Krüger, H., La Rosa, A., Liu, J., Miucci, A., Muenstermann, D., Nessi, M., Obermann, T., Pangaud, P., Perić, I., Pernegger, H., Quadt, A., Rieger, J., Ristic, B., Rozanov, A., Weingarten, J., Wermes, N.   +39 more
core   +2 more sources

Adjustment of Coatings Morphology and Particle Distribution of Layered Silicates by Freeze‐Drying for Improved Gas Barriers

Advanced Engineering Materials, EarlyView.
Freeze‐drying of layered silicate is the key to get coatings with superior gas barrier. Freeze‐drying of layered silicates modified with dodecylamine (DDA) is a highly effective technique for the preparation of barrier pigments that significantly mitigate the permeation of oxygen, water vapor, and hydrogen through polymer films containing these ...
Joshua Lommes, Moritz Bätcher, Andrea Deißenberger, Volkmar Stenzel, Andreas Hartwig   +4 more
wiley   +1 more source