Results 171 to 180 of about 61,075 (312)
Advanced Science, EarlyView.Single‐cell RNA sequencing reveals distinct immune responses to FLASH versus conventional dose rate irradiation in early radiation‐induced lung injury. FLASH irradiation reduces Ccrl2⁺ neutrophil infiltration, activates CD4⁺ CD40L⁺ Th cells, restrains pro‐inflammatory Mefv⁺ monocytes, and enhances epithelial repair via TGF‐β signaling, underscoring its
Hao Lu +10 more
wiley +1 more source
Surgical Reconstruction of Radiation Injuries. [PDF]
Adv Wound Care (New Rochelle), 2014 Fujioka M.
europepmc +1 more source
Nanomedicine‐Driven Modulation of Reductive Stress for Cancer Therapy
Advanced Science, EarlyView.This article introduces a novel therapeutic paradigm that deliberately induces reductive stress within tumor cells to exploit their unique biochemical vulnerabilities. It systematically reviews the underlying biological mechanisms, current detection and monitoring techniques, and emerging advanced nanotechnology platforms specifically designed to ...
Yumin Mao +8 more
wiley +1 more source
Advanced Science, EarlyView.Through metabolomic and transcriptomic analyses, a glutamine‐enriched, immunosuppressive microenvironment is identified in cervical squamous cell carcinoma (CSCC), highlighting the glutamine transporter SLC25A22 as a key regulator of glutamine metabolism, immune checkpoint activation, and CD8+ T‐cell cytotoxicity.
Tingting Ren +7 more
wiley +1 more source
Prophylactic glutamine protects the intestinal mucosa from radiation injury
, 1990 V. Suzanne Klimberg +11 more
openalex +1 more source
Advanced Science, EarlyView.Schematic model of CJP–TiN liposomes for gastric cancer (GC) treatment. Internalizing RGD peptide (iRGD) targets tumor cells, while Chlorin e6 (Ce6) generates reactive oxygen species (ROS). Jolkinolide B (JB) activates the PANoptosis pathway via caspase‐8, enhancing GC cell death and immune response, transforming “cold tumors” into “hot tumors” by ...
Chenhui Ma +14 more
wiley +1 more source
Radiation Exposure Induced Blood–Brain Barrier Injury via Mitochondria‐Mediated Sterile Inflammation
Advanced Science, EarlyView.This work describes a blood–brain barrier (BBB) microphysiological system (MPS) to explore the responses of BBB to radiation exposure. Following radiation exposure, obvious BBB comprise and brain endothelial injuries are detected. Mechanism study shows radiation induced significant sterile inflammation via mitochondrial dysfunction and cGAS‐STING ...
Peng Wang +6 more
wiley +1 more source
Radiation tolerance and the new biology: growth factor involvement in radiation injury to the lung
, 1992 Zvi Fuks, Ralph R. Weichselbaum
openalex +1 more source
Intra-rectal application of amifostine for prevention of late radiation rectal injury: preliminary results of a phase i dose escalation study [PDF]
, 2001 Irving Kaplan +7 more
openalex +1 more source