Results 231 to 240 of about 66,666 (245)

A dual life-saving approach: Thoracic endovascular aortic repair. [PDF]

Turk Gogus Kalp Damar Cerrahisi Derg
Tayfur K, Keleş Tayfur E.
europepmc   +1 more source

Polystyrene Microplastics Exposure Aggravates Clear Cell Renal Cell Carcinoma Progression via the NF‐κB and TGF‐β Signaling Pathways

Advanced Science, EarlyView.
This research provides the first comprehensive evidence that PS‐MPs exacerbate ccRCC progression by activating the NF‐κB and TGF‐β pathways. These findings establish PS‐MPs as an environmental risk factor for ccRCC progression and identify the NF‐κB and TGF‐β signaling as potential therapeutic targets to mitigate the adverse effects of ‐PS‐MPs exposure.
Shiqi Ye, Jianfeng Xiang, Siqi Zhou, Qintao Ge, Aihetaimujiang Anwaier, Kun Chang, Gang Wei, Jiahe Lu, Xi Tian, Shuxuan Zhu, Yuchen Jiang, Wei Zhang, Tingting Cai, Moran Xu, Dingwei Ye, Danfeng Xu, Tao Wang, Hailiang Zhang, Wenhao Xu   +18 more
wiley   +1 more source

Phocaeicola coprophilus‐Derived 6‐Methyluracil Attenuates Radiation‐Induced Intestinal Fibrosis by Suppressing the IDO1‐Kynurenine‐AHR Axis

Advanced Science, EarlyView.
IR‐induced dysbiosis depletes P. coprophilus and its metabolite 6‐methyluracil, leading to disinhibition of the IDO1‐Kyn‐AHR axis. This results in sustained fibroblast activation and collagen deposition, driving radiation induced intestinal fibrosis. ABSTRACT Therapeutic options for radiation‐induced intestinal fibrosis (RIF) remain limited. This study
Jiaxin Zhang, Zhen Wang, Shuang Li, Chao Luo, Han Li, Shengjie Ma, Pai Wang, Heshi Liu, Lijun Sun, Yue Yin, Weizhen Zhang, Quan Wang   +11 more
wiley   +1 more source

National Trends in Rock Climbing Injuries: A 10-Year Epidemiological Analysis of US Emergency Department Data (2014-2023). [PDF]

JB JS Open Access
Lin JQ, Khera JS, Furtado N, Saiz AM.
europepmc   +1 more source

Arginine Methylation Antagonizes TEAD3‐Mediated Repression to Promote Osteogenic Differentiation by Disrupting RUNX2‐Sequestrating Condensates

Advanced Science, EarlyView.
In the unmethylated state, TEAD forms stable, repressive condensates that sequester the osteogenic master regulator RUNX2. Arginine methylation of TEAD at R55 acts as a molecular brake, dissolving these condensates to release RUNX2 and activate the osteogenic program.
Lei Cao, Ruohui Han, Hui Xiong, Qian Li, Shaofei Tao, Xudong Wu, Dayong Liu   +6 more
wiley   +1 more source

Diagnostic and Surgical Planning Value of Computed Tomography (CT) in Adult Ankle Fractures: A Narrative Review. [PDF]

Cureus
Ghosh A.
europepmc   +1 more source

A Biomimetic Norepinephrine‐Loaded Aligned Mineralized Collagen Scaffold for Coordinated Neurovascular, Osteogenic, and Immunomodulatory Repair of Critical‐Sized Bone Defects

Advanced Science, EarlyView.
Inspired by the composition and structure of native bone tissue and its complex interplay of biological signals, a norepinephrine‐loaded biomimetic mineralized electrocompacted collagen scaffold (NE‐MEC) is developed capable of simultaneously supporting osteogenesis, neural repair, angiogenesis, and immune modulation.
Zhengyun Ren, Zhaojun Wu, Anhang Wu, Hui Zhang, Jiachen Lu, Jiahao Zhang, Jie Weng, Jinhua Zhang, Song Chen, Huan Tan, Tailin Guo   +10 more
wiley   +1 more source

Patterns and Prevention of Occupational Eye Injuries: A Narrative Review. [PDF]

Clin Ophthalmol
Vought V, Zarbin F, Vought R, Khouri AS.
europepmc   +1 more source

Patterns of thoracic injury in bomb blast victims: A retrospective radiological review. [PDF]

J Int Med Res
Ahmad MN, Abdullah M, Shaikh RH, Pervez R, Uddin MMZ, Nadeem N, Saleem A, Zafar U.   +7 more
europepmc   +1 more source

Musculoskeletal Occupational Injuries among Orthopedic Surgeons: Risk Factors and Insights from a Cross-Sectional Study. [PDF]

J Orthop Case Rep
Muthu S, Chellamuthu G, Chinnappan A, Vadranapu S, Jeyaraman N, Jeyaraman M.   +5 more
europepmc   +1 more source