Results 31 to 40 of about 65,131 (260)

Management of Radiation-induced Tissue Injuries: A Review of Current Treatment Strategies

open access: yesPlastic and Reconstructive Surgery, Global Open, 2023
Background:. Although radiation therapy remains an integral component in cancer treatment, the sequela of tissue damage can result in long-term morbidity and mortality for patients.
Richard Simman, MD, FACS, FACCWS   +4 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

Effectiveness of autologous cell products derived from adipose tissue for the treatment of severe local radiation injuries [PDF]

open access: yesСаратовский научно-медицинский журнал, 2014
Aim: to investigate the dynamics of ulcer surface healing depending on type of radiation ulcer and cell product in murine experimental model of severe local radiation injuries after exposure to X-rays. Material and Methods.
Eremin P.S.   +9 more
doaj  

Spatial and Volumetric Characteristics of Glioblastoma: Associations With Clinical Presentation and Survival

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We aim to comprehensively analyze how regional tumor and edema characteristics are associated with clinical presentations and survival outcomes in a large cohort of glioblastoma patients. Methods Patients with IDH‐wildtype glioblastoma who received brain MRI from 2010 to 2023 were included.
Daniel J. Zhou   +16 more
wiley   +1 more source

Transplantation of human umbilical cord mesenchymal stem cells repairs radiation-induced reproductive injury in male mice via improving mitochondrial function and attenuating oxidative stress

open access: yes陆军军医大学学报
Objective To investigate the ameliorative effect of human umbilical cord mesenchymal stem cells (hUC-MSCs) on radiation-induced reproductive damage in male mice and its potential mechanisms.
LI Jiangyi, LI Jiangyi, ZHENG Bo
doaj   +1 more source

Nutritional supplementation with arginine protects radiation-induced effects. An experimental study [PDF]

open access: yesActa Cirúrgica Brasileira, 2016
PURPOSE: To investigate the protective effect of L-arginine on the prostate (nonneoplasic) of rats with radiation-induced injury. METHODS: Twenty-nine Wistar rats, male adult, allocated into three groups: Control group (C) was not exposed to irradiation
Flavia Cristina Morone Pinto   +4 more
doaj   +1 more source

Stage‐Specific Patterns of Imaging and Non‐Motor Biomarkers in Spinocerebellar Ataxia Type 3

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Advancements in disease‐modifying therapies for spinocerebellar ataxia Type 3 (SCA3) underscore the need for robust biomarkers to monitor disease progression and evaluate treatment efficacy. Although motor phenotypes have been well characterized, less is known about non‐motor and imaging‐based features across different disease stages.
Chun Li   +17 more
wiley   +1 more source

An ultra-late maxillofacial cavity following multimodal treatment for adult head and neck rhabdomyosarcoma: a case report with a 16-year follow-up

open access: yesFrontiers in Oncology
ObjectiveTo report a rare case of a patient with adult rhabdomyosarcoma (RMS) in the craniofacial region who developed a very late-stage left maxillofacial cavity after 16 years of multimodal treatment, and to systematically investigate the potential ...
Wanhui Dong   +6 more
doaj   +1 more source

Efficacy of Prophylactic Anti-VEGF in Preventing Radiation Retinopathy: A Systematic Review and Meta-Analysis

open access: yesClinical Ophthalmology, 2023
Andi Arus Victor,1 Gitalisa Andayani,1 Ari Djatikusumo,1 Anggun Rama Yudantha,1 Mario Marbungaran Hutapea,1 Triana Hardianti Gunardi,2 Hannah Soetjoadi2 1Department of Ophthalmology, Faculty of Medicine, Universitas Indonesia, Dr.
Victor AA   +6 more
doaj  

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