Results 1 to 10 of about 3,894,991 (398)
DAMPs and radiation injury. [PDF]
The heightened risk of ionizing radiation exposure, stemming from radiation accidents and potential acts of terrorism, has spurred growing interests in devising effective countermeasures against radiation injury. High-dose ionizing radiation exposure triggers acute radiation syndrome (ARS), manifesting as hematopoietic, gastrointestinal, and ...
Yamaga S+4 more
europepmc +5 more sources
Deteriorative Effects of Radiation Injury Combined with Skin Wounding in a Mouse Model [PDF]
Radiation-combined injury (RCI) augments the risk of morbidity and mortality when compared to radiation injury (RI) alone. No FDA-approved medical countermeasures (MCMs) are available for treating RCI.
Li Wang+8 more
doaj +2 more sources
Compound Kushen Injection Protects Skin From Radiation Injury via Regulating Bim [PDF]
Background: Radiation-induced skin injury is a major side-effect observed in cancer patients who received radiotherapy. Thus identifying new radioprotective drugs for prevention or treatment of post-irradiation skin injury should be prompted.
Jianxiao Zheng+12 more
doaj +2 more sources
Co-Therapy of Pegylated G-CSF and Ghrelin for Enhancing Survival After Exposure to Lethal Radiation
Exposure to ionizing radiation (radiation injury, RI) in nuclear-related episode is evident to be life-threatening. RI occurs at levels of organs, tissues, cytosols, or nucleus. Their mechanisms are still not fully understood.
Juliann G. Kiang+7 more
doaj +1 more source
IntroductionBrain hemorrhage was found between 13 and 16 days after acute whole-body 9.5 Gy 60Co-γ irradiation (IR). This study tested countermeasures mitigating brain hemorrhage and increasing survival from IR.
Juliann G. Kiang+12 more
doaj +1 more source
Disulfiram Protects Against Radiation-Induced Intestinal Injury in Mice
Radiation-induced intestinal injury (RIII) occurs after high doses of radiation exposure. RIII restricts the therapeutic efficacy of radiotherapy in cancer and increases morbidity and mortality in nuclear disasters.
Qingwen Yuan+11 more
doaj +1 more source
BackgroundAt present, radiation therapy is widely used in clinical treatment of tumors. However, while radiation therapy damages tumor cells, it also injures surrounding normal tissues. Studies have shown that hydrogen is a potential radiation-protective
Yong WANG+6 more
doaj +1 more source
BackgroundIn the process of radiotherapy, when radiation kills tumor cells, it inevitably damages normal tissue cells. ObjectiveTo investigate the role of Toll-like receptor 4 (TLR4)/nuclear factor−kappa B (NF-κB) signaling pathway in the improvement of ...
Xiaoman CHEN+6 more
doaj +1 more source