Results 111 to 120 of about 3,894,991 (398)

Imaging Radiation Pneumonitis in a Rat Model of a Radiological Terrorism Incident [PDF]

, 2009
We have developed a rat model of single, sub-lethal thoracic irradiation. Our irradiation protocol is considered representative of exposures near the detonation site of a dirty bomb or small nuclear device.
Jacobs, Elizabeth R., Krenz, Gary S., Medhora, Meetha, Molthen, Robert C., Moulder, John E., Wu, QingPing   +5 more
core   +1 more source

Autophagy confers DNA damage repair pathways to protect the hematopoietic system from nuclear radiation injury

Scientific Reports, 2015
Autophagy is essentially a metabolic process, but its in vivo role in nuclear radioprotection remains unexplored. We observed that ex vivo autophagy activation reversed the proliferation inhibition, apoptosis and DNA damage in irradiated hematopoietic ...
Weiwei Lin, N. Yuan, Zhen Wang, Yan Cao, Yixuan Fang, Xin Li, Fei Xu, Lin Song, Jian Wang, Han Zhang, Lili Yan, Li Xu, Xiaoying Zhang, Suping Zhang, Jianrong Wang   +14 more
semanticscholar   +1 more source

Engineering Topographical Cues to Enhance Neural Regeneration in Spinal Cord Injury: Overcoming Challenges and Advancing Therapies

Advanced Functional Materials, EarlyView.
Spinal cord injury (SCI) poses significant challenges for regeneration due to a series of secondary injury mechanisms. How to use biomaterial approach to target the failed regeneration after SCI remains a critical challenge. This review systematically evaluates current strategies to optimize biomaterial topographies for neurite outgrowth, axonal ...
Wei Xu, Fenghui Wang, Joshua Stein, Siqiao Wang, Pengfei Jiang, Letao Yang, Liming Cheng, Ki‐Bum Lee   +7 more
wiley   +1 more source

Radiation-induced skin injury: pathogenesis, treatment, and management

Aging, 2020
Radiation-induced skin injury (RSI) refers to a frequently occurring complication of radiation therapy. Nearly 90% of patients having received radiation therapy underwent moderate-to-severe skin reactions, severely reducing patients' quality of life and ...
Xiaojing Yang, Hanru Ren, Xiaomao Guo, Chaosu Hu, J. Fu   +4 more
semanticscholar   +1 more source

Aptamer Functionalized Hydrogel Dressings for Post‐Surgery Tumor Recurrence Inhibition and Tissue Reconstruction

Advanced Functional Materials, EarlyView.
Post‐surgical tumor therapy struggles with recurrence and inefficient healing. Anti‐tumor DNA aptamer functionalized gelatin hydrogels, Apt‐GelMA, simultaneously address both issues by suppressing tumor regrowth via targeted tumor cell inhibition and enhancing wound healing through improved cell adhesion and migration. Their biocompatibility, stability,
Tianyue Li, Xin‐Yi Qian, Zi‐Yuan Li, Hao‐Wen Li, Poh‐Ching Tan, Chenghuizi Hu, Jiajun Jin, Shuang‐Bai Zhou, Qing‐Feng Li, He Tian, Junji Zhang, Itamar Willner   +11 more
wiley   +1 more source

Ghrelin, a novel therapy, corrects cytokine and NF-κB-AKT-MAPK network and mitigates intestinal injury induced by combined radiation and skin-wound trauma

Cell & Bioscience, 2020
Background Compared to radiation injury alone (RI), radiation injury combined wound (CI) further enhances acute radiation syndrome and subsequently mortality.
J. Kiang, Joan T. Smith, G. Cannon, Marsha N. Anderson, Connie Ho, M. Zhai, Wanchang Cui, Mang Xiao   +7 more
semanticscholar   +1 more source

Synthetic Bilirubin‐Based Nanomedicine Protects Against Renal Ischemia/Reperfusion Injury Through Antioxidant and Immune‐Modulating Activity

Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
BX‐001N, a polyethylene glycol‐conjugated bilirubin 3α nanoparticle, is the first GMP‐grade, synthetic bilirubin‐based nanomedicine. It effectively attenuates acute renal injury, facilitates subacute renal recovery, and suppresses chronic fibrosis after renal ischemia/reperfusion injury via anti‐oxidant and immune‐modulating activity.
Ji‐Jing Yan, Hyunjin Kim, Bomin Kim, Honglin Piao, Joon Young Jang, Tae Kyeom Kang, Wook‐Bin Lee, Dohyeon Kim, Seunghyun Jo, Duckhyang Shin, Sharif MD Abuzar, Myung L. Kim, Jaeseok Yang, Sangyong Jon   +13 more
wiley   +1 more source

Genetic Upregulation of Activated Protein C Mitigates Delayed Effects of Acute Radiation Exposure in the Mouse Plasma

Metabolites
Exposure to ionizing radiation, accidental or intentional, may lead to delayed effects of acute radiation exposure (DEARE) that manifest as injury to organ systems, including the kidney, heart, and brain. This study examines the role of activated protein
Shivani Bansal, Yaoxiang Li, Sunil Bansal, William Klotzbier, Baldev Singh, Meth Jayatilake, Vijayalakshmi Sridharan, José A. Fernández, John H. Griffin, Hartmut Weiler, Marjan Boerma, Amrita K. Cheema   +11 more
doaj   +1 more source

5,6,7,8-tetrahydroneopterin (NH4) Acts like an Endogenous Superoxide Dismutase

Pteridines, 1996
The protective effect of 5,6,7,8-tetrahydroneopterin (NH.) against radiation injury in mice was studied. (C57BL/6x A/J)F1 mice received whole body irradiation with a single fatal dose of 8.0 Gy X-ray.
Sawada Suguru, Morimoto Takeshi, Kito Tsuyoshi, Taguchi Osamu, Yasumura Mikio, Hirose Hajime   +5 more
doaj   +1 more source

RADIOLOGY OF UROLOGICAL COMPLICATIONS AFTER TREATMENT OF PELVIC TUMORS. PART II. URINARY LEAKS AND URETERAL INJURIES

Вестник рентгенологии и радиологии, 2017
Urinary leaks and ureteral injuries under treatment of pelvic tumors are the difficult and unsettled clinical diagnostic problem. For their radiodiagnostics using different imaging techniques, primarily computed tomography.
T. P. Berezovskaya, N. K. Silant’eva, O. G. Beketova   +2 more
doaj   +1 more source