Results 281 to 290 of about 560,406 (374)

Glycosylation Gene Signatures as Prognostic Biomarkers in Glioblastoma

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glioblastoma (GBM) is an aggressive brain tumor characterized by significant heterogeneity. This study investigates the role of glycosylation‐related genes in GBM subtyping, prognosis, and response to therapy. Methods We analyzed mRNA expression data and clinical information from The Cancer Genome Atlas (TCGA) and Gene Expression ...
Tong Zhao, Hongliang Ge, Chenchao Lin, Xiyue Wu, Jianwu Chen   +4 more
wiley   +1 more source

The feasibility of using intra-arterial cisplatin & radiation therapy for stage IV-T4 head/neck (H/N) squamous cell carcinoma in a multi-institutional setting: preliminary results of radiation therapy oncology group (RTOG) trial 9615

, 2000
Pattem Sampath Kumar, J. R. Harris, Robbins Kt, Paul H. Levine, Tine McCulloch, Robert A. Sofferman   +5 more
openalex   +1 more source

Radiation Oncology Residency Training in Saudi Arabia: Direction in Attaining Competencies. [PDF]

Cureus
Mohaimeed A, Alayed Y, Aljabab S, Julaidan B, Aldehaim M, Almomen F, Alswilem A, AlSuhaibani A.   +7 more
europepmc   +1 more source

An Analysis for IDH‐Mutant Grade 4 Astrocytoma Based on WHO CNS 5: Implication of Clinical Practice

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Purpose There is ongoing debate regarding the therapeutic approach and prognosis for IDH‐mutant grade 4 astrocytoma, a newly defined subtype of diffuse glioma in the 2021 WHO classification system for central nervous system tumors (WHO CNS 5). The aim of this study was to explore the clinical outcome and prognosticators for newly diagnosed IDH‐
Xianxin Qiu, Liping Liang, Lingchao Chen, Pengjie Hong, Wanzun Lin, Jiabing Liu, Zhirui Zhou, Wenjia Zhu, Tianqi Wu, Mingyuan Pan, Yihua Zhong, Jing Gao, Zhiyong Qin, Yang Wang   +13 more
wiley   +1 more source

Large language models for pretreatment education in pediatric radiation oncology: A comparative evaluation study. [PDF]

Clin Transl Radiat Oncol
Wawrzuta D, Napieralska A, Ludwikowska K, Jaruševičius L, Trofimoviča-Krasnorucka A, Rausis G, Szulc A, Pędziwiatr K, Poláchová K, Klejdysz J, Chojnacka M.   +10 more
europepmc   +1 more source

The Regulation of Trace Metal Elements in Cancer Ferroptosis

Advanced Biology, EarlyView.
The induction of ferroptosis inhibits tumor growth, enhances anticancer efficacy, and overcomes drug resistance. Recent evidence shows nonferrous metal elements play a role in ferroptosis. This review focuses on how trace metals regulate ferroptosis processes like iron accumulation, lipid peroxidation, and antioxidant defense.
Xiaoyan Wang, Yuanyuan Xue, Lei Chang, Xuena Zhu, Wenjun Liu, Tingbo Liang   +5 more
wiley   +1 more source

Best practice in radiation oncology: A project to train the trainers: Review of 2008-2023. [PDF]

Tech Innov Patient Support Radiat Oncol
Coffey M, Dickie C, Fidarova E, Karadža V, Scherer P, Leech M.   +5 more
europepmc   +1 more source

Electric Pulse Regulated MXene Based Nanozymes for Integrative Bioelectricity Immuno‐Cancer Therapy

Advanced Functional Materials, EarlyView.
MXenzyme‐mediated bioelectricity cancer therapy (MXenzyme‐BECT) enhances cancer cell death through irreversible depolarization, ion channel disruption, ROS generation, and immunogenic cell death. Computational simulations reveal the electrical mechanisms by which MXenzyme acts on single cells and support to predict treatment parameters. Next‐generation
Sanghee Lee, Seongchan Kim, Eui‐Sang Yu, Sian Lee, Min Jun Ko, Hyojin Lee, Dong‐Hyun Kim   +6 more
wiley   +1 more source

LLM-driven multimodal target volume contouring in radiation oncology. [PDF]

Nat Commun
Oh Y, Park S, Byun HK, Cho Y, Lee IJ, Kim JS, Ye JC.   +6 more
europepmc   +1 more source

H2O2‐Generating Advanced Nanomaterials for Cancer Treatment

Advanced Functional Materials, EarlyView.
H2O2‐generating nanoplatforms can exploit tumor redox imbalance for O2 and toxic reactive oxygen species generation, leading to hypoxia reversal, and apoptosis of cancer cells, respectively. This review highlights the mechanisms of these nanoplatforms, including exogenous H₂O₂ delivery, endogenous amplification, and metal peroxides, which leads to ...
Kiyan Musaie, Samin Abbaszadeh, Kik Marais, Vahideh Nosrati‐Siahmazgi, Saman Rezaei, Bo Xiao, Kamal Dua, Hélder A. Santos, Mohammad‐Ali Shahbazi   +8 more
wiley   +1 more source