Results 51 to 60 of about 360,530 (300)

Chinese expert consensus on the application of pegylated recombinant human granulocyte colony‐stimulating factor during concurrent chemoradiotherapy (2020 edition)

Precision Radiation Oncology, 2021
Jun Wang, Baosheng Li, Chinese Association for Therapeutic Radiation Oncologists, China Society for Radiation Oncology, Chinese Association of Radiation Therapy   +2 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

NIMG-49. A PROSPECTIVE, MULTI-CENTRE TRIAL OF FET-PET IN GLIOBLASTOMA PATIENTS - THE TROG 18.06 FIG STUDY: KEY ASPECTS OF IMAGING AND RADIATION ONCOLOGY CREDENTIALING [PDF]

, 2021
Eng‐Siew Koh, Roslyn J. Francis, Martin A. Ebert, Hui Gan, Sze Ting Lee, Eddie Lau, Alisha Moore, Andrew Grose, Alana Rossi, Sweet Ping Ng, June Yap, Tam Ly, Peter Lin, Mark B. Pinkham, Stanley Ngai, Christopher Yu, Peter Gorayski, Hien Le, Ian Kirkwood, Wilson Vallat, Farhan Syed, Dayanethee Krishna, Shahroz Khan, Suki Gill, Elizabeth R. Thomas, Michael Back, Elizabeth H Barnes, Bradford A. Moffat, Fiona E. Scott, Lucas Adda, Farshad Foroudi, Richard De Abreu Lourenço, Anna K. Nowak, Dale L. Bailey, Andrew M. Scott   +34 more
openalex   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

A three day coaching protocol for deep inspiration breath hold in left breast radiotherapy using active breathing control

Scientific Reports
The deep inspiration breath-hold (DIBH) technique is recommended for left-sided breast radiotherapy to reduce heart dose exposure. However, this technique introduces uncertainties due to possible anatomical variations across successive breath-holds ...
Siqi Jiang, Haokun Shi, Xi Ye, Jun Yang, Jian Zheng, Peiwei Wu, Qiang Ye, Shuanglai Qin, Wenjie Liu, Zuowei Hu, Yu Cai   +10 more
doaj   +1 more source

The Economic Impact of the COVID-19 Pandemic on Radiation Oncology Practice

, 2021
Carol Oliveira, Brooke E. Wilson, Ajay Aggarwal, Yolande Lievens, Danielle Rodin   +4 more
openalex   +1 more source

Biallelic Inactivation of NSD1 Associated With Carcinogenesis in Sotos Syndrome

Pediatric Blood &Cancer, EarlyView.
Nicholas A. Borja, Anuja Sule, Katie Ann McMullen, Aditi Dhir, Matthew D. Hall, Heather J. McCrea, Sakir Humayun Gultekin, Mustafa Tekin, Bradley Gampel   +8 more
wiley   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

FIRST RESULTS AND ASPECTS OF IN VIVO DOSIMETRY SYSTEM IMPLEMENTATION OF EXTERNAL RADIATION THERAPY IN TOMSK REGIONAL ONCOLOGY CENTER [PDF]

, 2020
Andrey V. Vertinskiy, L. G. Sukhikh, Evgeniia Sukhikh, Yana N. Sutygina   +3 more
openalex   +1 more source