Results 61 to 70 of about 931,154 (287)

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

Research of influence of technological processing parameters of protein-fat base for supply of sportsmen on activity of protease inhibitors [PDF]

open access: yes, 2017
The object of research is the biological value of the protein-fat base for athletes, workers of heavy physical labor, military personnel, depending on the conditions of its preliminary processing.
Belinska, Anna   +5 more
core   +1 more source

Ring artifacts correction in compressed sensing tomographic reconstruction

open access: yes, 2015
We present a novel approach to handle ring artifacts correction in compressed sensing tomographic reconstruction. The correction is part of the reconstruction process, which differs from classical sinogram pre-processing and image post-processing ...
Mirone, Alessandro, Paleo, Pierre
core   +3 more sources

Screening for lung cancer: A systematic review of overdiagnosis and its implications

open access: yesMolecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz   +12 more
wiley   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Silicon solar cells improved by lithium doping [PDF]

open access: yes, 1970
Results of conference on characteristics of lithium-doped silicon solar cells and techniques required for fabrication indicate that output of cells has been improved to point where cells exhibit radiation resistance superior to those currently in use ...
Berman, P. A.
core   +1 more source

Coherence in Spontaneous Radiation Processes [PDF]

open access: yesPhysical Review, 1954
In den letzten Jahren wurde das Problem der Anregung von gegenseitig abhängigen Zuständen atomarer Strahlungssysteme mit nachfolgender Emission einer spontanen kohärenten Strahlung von besonderer Wichtigkeit. Speziell die Erforschung der magnetischen Kernresonanz wurde dadurch gefördert (siehe \textit{E. L. Hahn} [Phys. Rev., II. Ser.
openaire   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Research of radiation resistance of hybrid integrated circuits

open access: yesТехнологія та конструювання в електронній апаратурі, 2008
The effect of fast electrons and neutrons has been studied on microsystems designed for measuring and stabilizing the temperature of primary converters of non-electrical quantities, whose transfer characteristics depend on temperature.
V. A. Mokritskij   +2 more
doaj  

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