Results 41 to 50 of about 673,372 (331)

Cellular transport of uranium and its cytotoxicity effects on CHO-k1 cells

Ecotoxicology and Environmental Safety, 2022
Uranium is a radioactive heavy metal and a significant public health concern; however, its associated underlying toxicological mechanisms remain largely unknown.
Liqun Huang, Shufang Li, Wenhua Zhou, Jie Gao, Jingjing Yin, Zhongwen Wang, Jianguo Li   +6 more
doaj   +1 more source

The micronucleus assay as a biological dosimeter of in vivo ionising radiation exposure [PDF]

, 2010
Biological dosimetry, based on the analysis of micronuclei (MN) in the cytokinesis-block micronucleus (CBMN) assay can be used as an alternative method for scoring dicentric chromosomes in the field of radiation protection.
Fenech, Michel, Thierens, Hubert, Vral, Anne   +2 more
core   +2 more sources

Parent‐to‐Child Information Disclosure in Pediatric Oncology

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Despite professional consensus regarding the importance of open communication with pediatric cancer patients about their disease, actual practice patterns of disclosure are understudied. Extant literature suggests a significant proportion of children are not told about their diagnosis/prognosis, which is purported to negatively ...
Rachel A. Kentor, Flora Hoodin, Michelle Byrd, Kristin A. Kullgren, Leah LaLonde, Lauren Benkoske, Patrick Smith, Dawn Carson, Karen MacDonald, Susumu Inoue, Brenda Kitchen, Kate Gowans, Gregory A. Yanik   +12 more
wiley   +1 more source

What evidence exists on the impact of anthropogenic radiofrequency electromagnetic fields on animals and plants in the environment: a systematic map

Environmental Evidence, 2023
Background Exposure to radiofrequency (RF) electromagnetic fields (EMF), particularly from telecommunications sources, is one of the most common and fastest growing anthropogenic factors on the environment.
Ken Karipidis, Chris Brzozek, Rohan Mate, Chhavi Raj Bhatt, Sarah Loughran, Andrew W Wood   +5 more
doaj   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

A bibliographical review on the concept of biological effects of ionizing radiation in Brazilian publications

Brazilian Journal of Radiation Sciences, 2021
At the end of the nineteenth century, with the use of ionizing radiation for the benefit of humanity in various sectors of society, its effects on human health became evident.
Gabriel De Lima Gonçalves, José Ubiratan Delgado, Fernando Barcellos Razuck   +2 more
doaj   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Hydrophobic modification and filtration performance of glass fiber filter material

Cailiao gongcheng
The closed-cycle process will generate a large number of radioactive aerosols, and its high humidity, high acidity, and high radioactivity lead to rapid failure and high replacement frequency of glass fiber high-efficiency filters.
CHEN Xin, YU Jie, LI Yongguo, LI Xin, LIN Zhongxin, PEI Jianlu, ZHENG Qin, LIU Tao, ZHANG Zhaochen, LIU Jingguo, ZHANG Jirong   +10 more
doaj   +1 more source

Shielding analysis in the design phase of the new Emergency Operation Facility for Tihange Nuclear Power Plant

EPJ Web of Conferences, 2017
In the framework of the design studies for a new Emergency Operation Facility (EOF) for Tihange NPP, radiation protection analyses are needed to comply with effective dose rate criteria.
Genard Gilles, Portal Romain, Bouchat Virginie, Vanderperre Serge   +3 more
doaj   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source