Results 71 to 80 of about 4,243,534 (405)

A bibliographical review on the concept of biological effects of ionizing radiation in Brazilian publications

open access: yesBrazilian Journal of Radiation Sciences, 2021
At the end of the nineteenth century, with the use of ionizing radiation for the benefit of humanity in various sectors of society, its effects on human health became evident.
Gabriel De Lima Gonçalves   +2 more
doaj   +1 more source

The nicotinamide hypothesis revisited—plant defense signaling integrating PARP, nicotinamide, nicotinic acid, epigenetics, and glutathione

open access: yesFEBS Letters, EarlyView.
Nicotinamide (NIC) and nicotinic acid (NIA) are proposed as stress signaling compounds in plants. Oxidative stress may lead to single strand breaks (SSB) in DNA, which activate poly(ADP‐ribose) polymerase (PARP). NIC and NIA are then formed from NAD. NIC and NIA can promote epigenetic changes leading to the expression of defense genes specific for the ...
Torkel Berglund, Anna B. Ohlsson
wiley   +1 more source

Aberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer

open access: yesMolecular Oncology, EarlyView.
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen   +12 more
wiley   +1 more source

Integrative effects based on behavior, physiology and gene expression of tritiated water on zebrafish

open access: yesEcotoxicology and Environmental Safety, 2021
Tritium is a water-soluble hydrogen isotope that releases beta rays during decay. In nature, tritium primarily exists as tritiated water (HTO), and its main source is nuclear power/processing plants.
Shengri Li   +13 more
doaj   +1 more source

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

open access: yesMolecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova   +18 more
wiley   +1 more source

Shielding analysis in the design phase of the new Emergency Operation Facility for Tihange Nuclear Power Plant

open access: yesEPJ Web of Conferences, 2017
In the framework of the design studies for a new Emergency Operation Facility (EOF) for Tihange NPP, radiation protection analyses are needed to comply with effective dose rate criteria.
Genard Gilles   +3 more
doaj   +1 more source

Molecular imaging predicts trastuzumab‐deruxtecan (T‐DXd) response in head and neck cancer xenograft models

open access: yesMolecular Oncology, EarlyView.
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed   +8 more
wiley   +1 more source

Hydrophobic modification and filtration performance of glass fiber filter material

open access: yesCailiao gongcheng
The closed-cycle process will generate a large number of radioactive aerosols, and its high humidity, high acidity, and high radioactivity lead to rapid failure and high replacement frequency of glass fiber high-efficiency filters.
CHEN Xin   +10 more
doaj   +1 more source

A revised compartmental model for biokinetics and dosimetry of 2-[18F]FDG

open access: yesEJNMMI Physics, 2023
Background The aim was to review available biokinetic data, collect own experimental data, and propose an updated compartmental model for 2-[18F]FDG in the frame of the revision of the ICRP report on dose coefficients for radiopharmaceuticals used in ...
Alexandra Kamp   +5 more
doaj   +1 more source

Hazards protection for space suits and spacecraft [PDF]

open access: yes, 1990
A flexible multi-layered covering article for protection against the hazards of exposure to the environment of outer space is disclosed. The covering includes an outer layer section comprising an outermost lamina of woven expanded tetrafluoroethylene ...
Dawn, Frederic S., Kosmo, Joseph J.
core   +1 more source

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