Results 191 to 200 of about 125,369 (239)

Thermally Gated Dual‐Cascade Nanozyme for Enhanced Mild‐Temperature Photothermal Therapy

Advanced Science, EarlyView.
A thermo‐responsive cascade nanozyme (Ru‐GOx‐PNN) synergistically enhances mild photothermal therapy by dual suppression of HSP70 through ROS‐induced lipid peroxidation and ATP depletion. This intelligent system effectively overcomes thermotolerance and amplifies apoptosis, offering a safe and precise strategy for tumor treatment.
Shuyu Wang, Shenghui Wang, Mengyuan Cao, Lulu Wang, Wei Jiang, Xiyun Yan, Ying Liu, Bing Jiang   +7 more
wiley   +1 more source

Phocaeicola coprophilus‐Derived 6‐Methyluracil Attenuates Radiation‐Induced Intestinal Fibrosis by Suppressing the IDO1‐Kynurenine‐AHR Axis

Advanced Science, EarlyView.
IR‐induced dysbiosis depletes P. coprophilus and its metabolite 6‐methyluracil, leading to disinhibition of the IDO1‐Kyn‐AHR axis. This results in sustained fibroblast activation and collagen deposition, driving radiation induced intestinal fibrosis. ABSTRACT Therapeutic options for radiation‐induced intestinal fibrosis (RIF) remain limited. This study
Jiaxin Zhang, Zhen Wang, Shuang Li, Chao Luo, Han Li, Shengjie Ma, Pai Wang, Heshi Liu, Lijun Sun, Yue Yin, Weizhen Zhang, Quan Wang   +11 more
wiley   +1 more source

Polyzwitterionic Organohydrogel and Soft Composite with Tunable Sol–Gel Properties Enabling On‐Demand Functionalization with Colloids

Advanced Science, EarlyView.
Poly[2‐(methacryloyloxy)ethyl]dimethyl‐(3‐sulfopropyl)ammonium hydroxide‐based organohydrogels are formed via nonsolvent‐induced gelation, featuring tunable viscoelasticity. Functional fillers (MXene nanosheets, magnetic NdFeB microparticles) enable electrical, magnetic, and mechanical responsiveness for applications in mechano‐tunable electromagnetic ...
Ziyue Miao, Xiaodan Hong, Olli Ikkala, Zhong‐Peng Lv, Bo Peng   +4 more
wiley   +1 more source

Unveiling a Stable Polysulfide Transport Framework in a Fluorine‐Free Li‐S Batteries

Advanced Science, EarlyView.
This work unveils a lithium thiophosphate reaction pathway activated by trigger P2S5 units, which initiate fast self‐assembly and shift the system away from conventional Li‐S reactions. The reversible Li‐P‐S framework delivers stability, safety, and high energy density, while enabling a distinct solid‐liquid hybrid electrochemical mode that provides a ...
Feng‐Yu Wu, Po‐Wei Chi, Phillip M. Wu, Maw‐Kuen Wu   +3 more
wiley   +1 more source

Heterointerface‐Functionalized Photoelectric Response of Metal‐Oxide Schottky Photodiode for Intelligent Fire Detection

Advanced Science, EarlyView.
A heterointerface‐functionalized Schottky photodiode (HF‐SPD) is developed to explore the photoelectric capabilities of low‐temperature oxide semiconductors. Besides the remarkable UV detection capability, the bias‐tunable photo response endows HF‐SPD with the unique wavelength selectivity.
Yuyang Cai, Zhiwei Zheng, Zhiwu Zhong, Yuhan Zhang, Tengyan Huang, Yucheng Cao, Dawei Zheng, Yen Hung Lin, Fion Sze Yan Yeung, Kuan‐Chang Chang, Jie Chen, Hoi Sing Kwok, Lei LU, Yufeng Jin   +13 more
wiley   +1 more source

Precision‐Engineered Silver Single‐Atom Carbon Dot Nanozymes for Theranostic Management of Acute Kidney Injury

Advanced Science, EarlyView.
Mitochondria‐targeted silver single‐atom carbon dot (T‐AgSA‐CDs) nanozymes enable dual SOD/GPx‐like ROS scavenging, real‐time imaging, and therapeutic effects for acute kidney injury (AKI). Atomically dispersed Ag sites synergize with carbon dots to restore renal redox hemostasis, protect mitochondrial function, mitigate inflammation, facilitate post ...
Tianle Tang, Jun Zhang, Yan Wang, Guoping Chen, Kehui Yuan, Yuan He, Chenchen Li, Sumaira Hanif, Yang Yang, Yanli Wang, Pir Muhammad   +10 more
wiley   +1 more source

CRISPR‐Cas9‐Loaded Theranostic Liposomes for Enhancing Radiosensitization of Prostate Cancer through POLD4 Gene Editing under Real‐Time MRI Monitoring

Advanced Science, EarlyView.
This study identifies POLD4 as a potential prostate cancer radiosensitization target through transcriptome sequencing. By encapsulating POLD4‐targeted CRISPR/Cas9 plasmids and USPIONs in cationic liposomes, an MRI‐monitored gene‐editing platform is established.
Xuhui Fan, Ruru Zhang, Linjun Yang, Shixiong Chen, Meijuan He, Yongqiang Wang, Linjie Huang, Jianfeng Zeng, Shuwang Wu, Mingyuan Gao, Han Wang   +10 more
wiley   +1 more source

Synergistic Effects of Additive Engineering in Enhancing the Performance of Sn–Pb Perovskite Thin‐Film Transistors and Derived Logic Circuits

Advanced Science, EarlyView.
An additive engineering strategy employing 4,8‐dihydrobenzo[1,2‐b:4,5‐b′]dithiophen‐4,8‐dione (BDTD) is utilized to passivate bulk defects, regulate crystallization dynamics, and suppress Sn4+ formation in Sn–Pb perovskite thin‐film transistors. The incorporation of BDTD yields a substantial enhancement in electrical performance, increasing the hole ...
Zeeshan Alam Ansari, Abhishek Kumar, Soumallya Banerjee, Chintam Hanmandlu, Anjali Thakran, Yu‐Te Chen, Po‐Yu Yang, Shenghan Li, Chun‐Wei Pao, Yun‐Chorng Chang, Chu‐Chen Chueh, Chih‐Wei Chu   +11 more
wiley   +1 more source

Cell‐Free DNA‐Based Theranostics for Inflammatory Disorders

Advanced Science, EarlyView.
Summary on the dual potential of cfDNA as biomarkers and therapeutic targets for inflammatory disorders. Figure was created with BioRender.com. ABSTRACT Inflammatory disorders are characterized by immune‐mediated inflammatory cascades that can affect multiple organs.
Jiatong Li, Yumei Wang, Xiaoxi Fan, Miao Xu, Jiawen Li, Wenfei Tan, Jianxiang Zhang, Heran Li   +7 more
wiley   +1 more source

Electrode Engineering for High‐Durability Variable‐Emissivity Devices Based on Reversible Copper Electrodeposition

Advanced Science, EarlyView.
An Ir‐based reversible copper electrodeposition variable‐emissivity device achieved over 8000 cycles with just 11% radiative temperature variation decay. This stability stems from Ir's inherent inertness, high conductivity, and strength, which collectively suppress cracking and corrosion.
Runyun He, Tianwen Liu, Liqiang Zhang, Tuoyu Liu, Dan Tang, Wenxia Zhang, Jundong Tao, Tingting Shi, Yijing Song, Haifeng Cheng, Yao Zhang, Dongqing Liu   +11 more
wiley   +1 more source