Results 241 to 250 of about 594,818 (309)

NNMT Orchestrates Metabolic‐Epigenetic Reprogramming to Drive Macrophage‐Myofibroblast Transition in Hypertrophic Scarring

Advanced Science, EarlyView.
In macrophage‐myofibroblast transition, upregulated NNMT depletes S‐Adenosylmethionine‌ (SAM) and nicotinamide adenine dinucleotide(NAD+), thereby triggering epigenetic reprogramming via Histone H3 Lysine 27 acetylation (H3K27ac) accumulation at the promoter region of master transcription factor Prrx1.
Xiwen Dong, Weinan Guo, Yuxuan Qian, Wenyan Jin, Xiaozhen Li, Jingyuan Yang, Qingrong Ni, Shuang Wu, Fanni Li, Hua Wang, Chunying Li, Hong Cai   +11 more
wiley   +1 more source

Initial three- and half-year machine performance assessment of a superficial radiation therapy unit. [PDF]

J Appl Clin Med Phys
Lee YC, Romaguera W, Davis SD, Wieczorek DJ, Chaswal V, Tolakanahalli R, Mehta MP, Kalman NS, Gutierrez AN.   +8 more
europepmc   +1 more source

Biocatalytic Nanoregulators Restore Joint Redox‐Immune Homeostasis in Rheumatoid Arthritis

Advanced Science, EarlyView.
Mesenchymal stem cell‐derived extracellular vesicles (EVs) coat ruthenium‐loaded metal‐organic frameworks (Ru@ZrMOF), creating a targeted therapeutic (Ru@ZrMOF/EVs). This platform scavenges ROS, generates oxygen, and polarizes macrophages from M1 to M2, alleviating inflammation, inhibiting pannus, promoting cartilage repair, and downregulating HIF‐1α ...
Xingheng Wang, Jianbo Huang, Shuwei Zhang, Sujiao Cao, Fangxue Du, Liqiang Zhou, Li Qiu, Yuanjiao Tang   +7 more
wiley   +1 more source

Monte Carlo simulations of geometric deformation of Harrison-Anderson-Mick applicators used in intraoperative radiation therapy. [PDF]

J Appl Clin Med Phys
Insley B, Bocian B, Beddar S, Reiazi R, Jensen PJ, Martin-Paulpeter RM, Niedzielski JS, Flint D, Sawakuchi GO, Perles LA.   +9 more
europepmc   +1 more source

Radiation therapy in the treatment of pancreatoblastoma: a narrative review. [PDF]

J Yeungnam Med Sci
Katano A.
europepmc   +1 more source

Stereotactic body radiation therapy in patients with unresectable hepatocellular carcinoma and portal vein tumor thrombosis. [PDF]

World J Hepatol
Khosla D, Gade VKV, Kapoor R, Singh G, Singh R, Taneja S, Premkumar M, Kalra N, De A, Bhujade H, Verma N, Duseja A, Gupta R.   +12 more
europepmc   +1 more source

Radioprotectors & mitigators in radiation therapy: Harnessing diverse pathways for optimizing clinical outcomes. [PDF]

Indian J Med Res
Palkar PA, John G, Chekuri G, Chatterjee A, Kunwar A, Goda JS.   +5 more
europepmc   +1 more source

A phase II study of anlotinib plus whole brain radiation therapy for patients with NSCLC with multiple brain metastases

Dayong Gu, Hongliang Yu, Naixin Ding, Jianhua Xu, Pudong Qian, Jun Zhu, Ming Jiang, Tao Hua, Xiangzhi Zhu   +8 more
openalex   +1 more source

The impact of radiation therapy on thyroid function in patient with head and neck tumors

Firas Fekri Najeeb Al-Taweel, S. Kadhim
openalex   +1 more source

A Clinical Workflow for Evaluating Dose to Organs at Risk After Biology-Guided Radiation Therapy Delivery. [PDF]

Cancers (Basel)
Banks TI, Shen C, Godley AR, Park YK, Prasad R, Ravikiran M, Badiyan SN, Dan T, Garant A, Timmerman R, Jiang S, Cai B.   +11 more
europepmc   +1 more source