Advanced Materials, EarlyView.Bioorthogonal chemistry was applied to intracellularly photoactivate Doxorubicin (Dox) using gold nanostars (AuNSt) and near‐infrared (NIR) light. Two prodrugs were used: one photoactivatable, masked with 2‐nitrobenzyl carbamate (proDox1) and another photolabile, masked with 2‐nitrobenzyl diol (proDox2), which was attached to the AuNSt surface.
Juan José Esteve‐Moreno +15 more
wiley +1 more source
Using Time-Staged Palliative Conventional Radiation Therapy Followed by Stereotactic Body Radiation Therapy in Malignant Epidural Extension for a Nonsurgical Candidate. [PDF]
Adv Radiat OncolPatel RK +8 more
europepmc +1 more source
Spatially Programmable Electroadhesive Enables In Situ Site‐Selective Functional Coupling
Advanced Materials, EarlyView.A light‐activated, in situ spatially programmable bioadhesive (STICH) enables microscale, site‐selective integration of bioelectronic devices with wet tissue. It achieves robust mechanical bonding and low‐impedance electrical coupling, enabling reconfigurable neuromodulation and directional electromechanical sensing in vivo and ex vivo.
Yuting Guo +12 more
wiley +1 more source
Correction: BDNF augmentation reverses cranial radiation therapy-induced cognitive decline and neurodegenerative consequences. [PDF]
Acta Neuropathol CommunEl-Khatib SM +10 more
europepmc +1 more source
Optoacoustic‐Guided Magnetic Microrobot Platform for Precision Drug Delivery
Advanced Materials, EarlyView.Optoacoustically guided FePt@ZIF‐8‐based microrobots are designed with high drug loading capacity, controllable locomotion, and deep‐tissue imaging capability. By integrating navigation, drug release, and real‐time monitoring into a single platform, they provide a versatile tool for precise intervention, opening new possibilities for treating ...
Fan Wang +12 more
wiley +1 more source
Dosimetric and hematological toxicity analyses of bone marrow-sparing intensity-modulated radiation therapy for patients with cervical cancer treated with extended-field radiation therapy. [PDF]
Precis Radiat OncolWang JN +10 more
europepmc +1 more source
Advanced Materials, EarlyView.This review summarizes recent advances in metal‐based nanomaterials (MBNs) as multifunctional platforms for next‐generation diagnostics and nanodynamic therapies (NDTs), highlighting their structural tunability, diverse therapeutic modalities, and broad biomedical applications in oncology and infectious disease control.
Qihang Ding +11 more
wiley +1 more source
Initial experience of spatially fractionated lattice radiation therapy for palliative treatment of pediatric bulky tumors. [PDF]
Front OncolZhang H +6 more
europepmc +1 more source
Advanced Materials, EarlyView.This study introduces glutathione‐stabilized gold nanoparticles for targeted lithium delivery (LiG‐AuNPs), enabling the controlled modulation of Glycogen Synthase Kinase‐3 (GSK‐3β). These non‐toxic, 2‐nm particles release lithium intracellularly, effectively inhibiting GSK‐3β in the brain without significant plasma lithium alterations.
Antonio Buonerba +20 more
wiley +1 more source