Results 71 to 80 of about 1,121,145 (324)

CT Derived Hounsfield Unit: An Easy Way to Determine Osteoporosis and Radiation Related Fracture Risk in Irradiated Patients

Frontiers in Oncology, 2020
Background: We aimed to evaluate osteoporosis, bone mineral density, and fracture risk in irradiated patients by computerized tomography derived Hounsfield Units (HUs) calculated from radiation treatment planning system.Methods: Fifty-seven patients ...
Gokhan Yaprak, Cengiz Gemici, Ozgur O. Seseogullari, Irem S. Karabag, Nilsu Cini   +4 more
doaj   +1 more source

In vivo dose measurement using TLDs and MOSFET dosimeters for cardiac radiosurgery. [PDF]

, 2012
In vivo measurements were made of the dose delivered to animal models in an effort to develop a method for treating cardiac arrhythmia using radiation. This treatment would replace RF energy (currently used to create cardiac scar) with ionizing radiation.
Blanck, Oliver, Dieterich, Sonja, Gardner, Edward, Iwamura, Alyson, Maguire, Patrick, Steel, James, Sumanaweera, Thilaka   +6 more
core   +2 more sources

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Neuro-Dynamic Programming for Radiation Treatment Planning [PDF]

, 2002
In many cases a radiotherapy treatment is delivered as a series of smaller dosages over a period of time. Currently, it is difficult to determine the actual dose that has been delivered at each stage, precluding the use of adaptive treatment plans ...
Ferris, Michael C., Voelker, Meta M.
core   +1 more source

Salvage Fractionated Stereotactic Re-irradiation (FSRT) for Patients with Recurrent High Grade Gliomas Progressed after Bevacizumab Treatment [PDF]

, 2017
Purpose/Objectives: Bevacizumab failure is a major clinical problem in the manage- ment of high grade gliomas (HGG), with a median overall survival of less than 4 months (m).
Andrews MD, David W., Bar-Ad, Voichita, Bhamidipati, Deepak, Blomain, Erik S, Dan, Tu, Evans, James J., Farrell, MD, Christopher J, Glass, MD, Jon, Judy, MD, Kevin, Kim, Lyndon, Palmer, Joshua, Shi, Wenyin, Siglin, Joshua, Wang, Yang, Werner-Wasik, Maria   +14 more
core   +2 more sources

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

MR‐based treatment planning in radiation therapy using a deep learning approach

Journal of Applied Clinical Medical Physics, 2019
Purpose To develop and evaluate the feasibility of deep learning approaches for MR‐based treatment planning (deepMTP) in brain tumor radiation therapy. Methods and materials A treatment planning pipeline was constructed using a deep learning approach to ...
Fang Liu, P. Yadav, A. Baschnagel, A. McMillan   +3 more
semanticscholar   +1 more source

Master Breast Radiation Planning: Simple Guide for Radiation Oncology Residents

Advances in Radiation Oncology
This article focuses on various aspects of breast radiation treatment planning, from simulation to field design. It covers the most common techniques including tangents, mono isocentric, dual isocentric, electron-photon match, and VMAT. This can serve as
Mona Arbab, MD, MEd, Romona Frame, MS, Prasanna Alluri, MD, PhD, David Parsons, PhD, Mu-Han Lin, PhD, Jennifer Cleaton, MS, Asal Rahimi, MD   +6 more
doaj   +1 more source

Lung volume irradiation procedures in patients with pneumonia during COVID-19 infection – physical aspects of treatment planning and dosimetry

Nowotwory, 2021
INTRODUCTION: The paper presents an original, used in our Institute, method of lung volume irradiation in patients with pneumonia during COVID-19 infection.
Krzysztof Ślosarek, Adam Gądek, Łukasz Sroka, Łukasz Dolla, Andrzej Biały, Michał Radwan, Dawid Bodusz, Michał Nachlik, Tomasz Rutkowski, Jerzy Jaroszewicz   +9 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source