Results 101 to 110 of about 786,111 (330)

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

open access: yesFEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Analysis of Global and Site-Specific Radiation Damage in Cryo-EM [PDF]

open access: bronze, 2018
Johan Hattne   +7 more
openalex   +1 more source

Anticancer sensitivities and biological characteristics of HCT116 cells resistant to the selective poly(ADP‐ribose) glycohydrolase inhibitor

open access: yesFEBS Open Bio, EarlyView.
We analyzed alterations of PAR metabolism‐related proteins in PARG inhibitor‐resistant HCT116RPDD cells. Although PARG levels remained unchanged, HCT116RPDD cells exhibited reduced PARP1 and ARH3 expression and elevated PAR levels. Interestingly, HCT116RPDD cells exhibited slightly elevated intracellular NAD+/NADH and ATP levels. Our findings suggest a
Kaede Tsuda, Yoko Ogino, Akira Sato
wiley   +1 more source

Radiated relics [PDF]

open access: yesProceedings of the National Academy of Sciences, 2013
“The history of the atomic age is intertwined with that of photography. Uranium’s radioactivity was discovered through a photograph,” says Elin O’Hara Slavick. She is the first American to photograph objects from the Hiroshima Peace Memorial Museum that were exposed to an atomic blast.
openaire   +2 more sources

Members of the Candidate Phyla Radiation are functionally differentiated by carbon- and nitrogen-cycling capabilities [PDF]

open access: gold, 2017
Robert Danczak   +5 more
openalex   +1 more source

Case of a 35‐Year‐Old Man With Pain With Sneezing and Leg Weakness Causing Collapse

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT This case details a 35‐year‐old man with no past medical history who presents with acute paraparesis and urinary retention in the setting of progressive paresthesias and weakness of his lower and upper extremities over several months. He was found to have longitudinally extensive transverse myelitis involving the cervical to mid‐thoracic cord ...
Joey Hsu   +3 more
wiley   +1 more source

People Living with HIV's Worry That the COVID-19 Health Crisis Could Impact Long-Term HIV Care: Lessons From the French Context for Future Disease Epidemics

open access: yesJournal of the International Association of Providers of AIDS Care
Background: In 2020, people living with HIV (PLHIV) in France were worried that the COVID-19 health crisis would lead to long-term changes in their HIV care.
M. Salcedo PhD   +11 more
doaj   +1 more source

DNA-Platinum Thin Films for Use in Chemoradiation Therapy Studies

open access: yesBioinorganic Chemistry and Applications, 2012
Dry films of platinum chemotherapeutic drugs covalently bound to plasmid DNA (Pt-DNA) represent a useful experimental model to investigate direct effects of radiation on DNA in close proximity to platinum chemotherapeutic agents, a situation of ...
Mohammad Rezaee   +3 more
doaj   +1 more source

A novel 3D human glioblastoma cell culture system for modeling drug and radiation responses [PDF]

open access: hybrid, 2016
Natividad Gomez-Roman   +4 more
openalex   +1 more source

Lesion Location and Functional Connections Reveal Cognitive Impairment Networks in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive impairment, fatigue, and depression are common in multiple sclerosis (MS), potentially due to disruption of regional functional connectivity caused by white matter (WM) lesions. We explored whether WM lesions functionally connected to specific brain regions contribute to these MS‐related manifestations.
Alessandro Franceschini   +7 more
wiley   +1 more source

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