Results 131 to 140 of about 2,520,292 (373)

Development of 4T1 breast cancer mouse model system for preclinical carbonic anhydrase IX studies

open access: yesFEBS Open Bio, EarlyView.
Carbonic anhydrase IX (CAIX) is a well‐recognised therapeutic target and prognostic biomarker in cancer. We developed and characterised a robust murine breast cancer model system that is suitable for CAIX studies in vitro and in vivo—it comprises both CAIX‐positive and CAIX‐negative controls and provides a solid platform for the comprehensive ...
Zane Kalniņa   +13 more
wiley   +1 more source

Deterministic evaluation of safety parameters and neutron flux spectra in the MNSR research reactor using DRAGON-4 code

open access: yesJournal of Radiation Research and Applied Sciences, 2018
Comparative studies for conversion of the fuel from high enriched uranium (HEU) to low enriched uranium (LEU) in the reactor (MNSR) were performed using DRAGON code deterministic. In this work the HEU fuel (UAl4-Al, 90% enriched with Al-clad) and LEU (12.
Jamal Al Zain   +3 more
doaj  

Identifying prognostic targets in metastatic prostate cancer beyond AR

open access: yesFEBS Open Bio, EarlyView.
Genome‐wide functional screens combined with a large gene expression database and clinical outcomes can identify new therapeutic vulnerabilities in prostate cancer. Eight potentially druggable targets demonstrated strong dependency in cell lines, were associated with worse prognosis clinically, and showed evidence of protein expression in prostate ...
Emily Feng   +13 more
wiley   +1 more source

DNA-Platinum Thin Films for Use in Chemoradiation Therapy Studies

open access: yesBioinorganic Chemistry and Applications, 2012
Dry films of platinum chemotherapeutic drugs covalently bound to plasmid DNA (Pt-DNA) represent a useful experimental model to investigate direct effects of radiation on DNA in close proximity to platinum chemotherapeutic agents, a situation of ...
Mohammad Rezaee   +3 more
doaj   +1 more source

DNA Damage and Repair in Plants under Ultraviolet and Ionizing Radiations

open access: yesTheScientificWorldJournal, 2015
Being sessile, plants are continuously exposed to DNA-damaging agents present in the environment such as ultraviolet (UV) and ionizing radiations (IR). Sunlight acts as an energy source for photosynthetic plants; hence, avoidance of UV radiations (namely,
S. Gill   +4 more
semanticscholar   +1 more source

Is Gravitational Radiation a Radiation of the Same Level as Electromagnetic Radiation?

open access: yesJournal of Modern Physics, 2014
The notion of gravitational radiation as a radiation of the same level as the electromagnetic radiation is based on the theoretically proven and experimentally confirmed facts of the existence of stationary states of an electron in its gravitational field, characterized by the gravitational constant K = 1042 G (G is Newtonian gravitational constant ...
I. S. Fisenko, S. I. Fisenko
openaire   +3 more sources

Preparation and characterization of renal cell peptides from fetal rats for their antitumor activity

open access: yesFEBS Open Bio, EarlyView.
This study aimed to prepare renal cells (RCs) from fetal rats which were digested by enzymes. Candidate peptides RCPs were characterized by capillary HPLC and MS and their bioactivity was predicted using peptideranker. The predicted top 10 bioactive peptides were synthesized.
Zhe Zhang   +6 more
wiley   +1 more source

Method of remotely characterizing thermal properties of a sample [PDF]

open access: yes, 1992
A sample in a wind tunnel is radiated from a thermal energy source outside of the wind tunnel. A thermal imager system, also located outside of the wind tunnel, reads surface radiations from the sample as a function of time.
Heath, D. Michele   +4 more
core   +1 more source

On the complexity of triggering evolutionary radiations.

open access: yesNew Phytologist, 2015
Recent developments in phylogenetic methods have made it possible to reconstruct evolutionary radiations from extant taxa, but identifying the triggers of radiations is still problematic.
Y. Bouchenak‐Khelladi   +4 more
semanticscholar   +1 more source

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