Results 41 to 50 of about 2,431 (219)

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Is OSSO a Significant Contributor to the Unknown UV Absorber in Venus' Atmosphere?

Geophysical Research Letters
It has been proposed that two isomers of the SO dimer (cis‐ and trans‐OSSO) are candidates for the unknown UV absorber in Venus' atmosphere because they have a good spectral match with the absorber, despite the low concentrations predicted by 1D ...
Joanna V. Egan, Wuhu Feng, Alexander D. James, James Manners, Daniel R. Marsh, Sébastien Lebonnois, Franck Lefèvre, Aurélien Stolzenbach, John M. C. Plane   +8 more
doaj   +1 more source

Measurement errors in cirrus cloud microphysical properties [PDF]

Annales Geophysicae, 1998
The limited accuracy of current cloud microphysics sensors used in cirrus cloud studies imposes limitations on the use of the data to examine the cloud's broadband radiative behaviour, an important element of the global energy balance.
H. Larsen, J.-F. Gayet, G. Febvre, H. Chepfer, G. Brogniez   +4 more
doaj   +1 more source

Radiative Processes and Jet Modification at the EIC [PDF]

Probing Nucleons and Nuclei in High Energy Collisions, 2020
Proceedings of the of the INT program "Probing Nucleons and Nuclei in High Energy Collisions (INT 18-3)" 4 pages, 2 ...
openaire   +2 more sources

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Intrapulse Spectral Evolution in Photospheric Gamma-Ray Bursts

The Astrophysical Journal
Photons that decouple from a relativistic jet do so over a range of radii, leading to a spreading in arrival times at the observer. Therefore, changes to the comoving photon distribution across the decoupling zone are encoded in the emitted signal.
Filip Alamaa
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

The early summertime Saharan heat low: sensitivity of the radiation budget and atmospheric heating to water vapour and dust aerosol [PDF]

Atmospheric Chemistry and Physics, 2018
The Saharan heat low (SHL) is a key component of the west African climate system and an important driver of the west African monsoon across a range of timescales of variability.
N. K. Alamirew, M. C. Todd, C. L. Ryder, J. H. Marsham, J. H. Marsham, Y. Wang   +5 more
doaj   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source