Results 141 to 150 of about 813,912 (244)

Reproductive Challenges of the Ageing Female: A Comprehensive Narrative Review

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Changes in societal norms over the last few decades have resulted in novel family planning trends, notably delayed childbearing and increased maternal age at the birth of the first child. Despite advances in reproductive medicine, ageing poses significant challenges.
Sofia Bitzika, Meletios P. Nigdelis, Angelos Daniilidis, Erich‐Franz Solomayer, Irene Lambrinoudaki, Efstratios M. Kolibianakis, Dimitrios G. Goulis   +6 more
wiley   +1 more source

Experiences of Women and Clinicians During the Introduction of Uterine Transplantation to the UK: A Qualitative Case Study

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To explore the experiences of women and clinicians during the introduction of uterine transplantation (UTx) to the UK. Design A qualitative study utilising prospective case study methodology (interviews and observations) over 6 years.
Daisy Elliott, Richard J. Smith, Maeve Coyle, Rhiannon Macefield, Saliha Vali, Anni King, Natalie Blencowe, Cynthia Ochieng, Christin Hoffmann, Isabel Quiroga, Ben P. Jones, Ariadne L'Heveder, Kerry N. L. Avery, Jane M. Blazeby   +13 more
wiley   +1 more source

Comparative Efficacy of Elinzanetant Versus Other Non‐Hormonal Pharmaceutical Therapies for the Treatment of Moderate‐to‐Severe Vasomotor Symptoms Associated With Menopause: A Network Meta‐Analysis

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Background Elinzanetant, a novel, dual neurokinin‐targeted therapy, has been approved in various geographies for the treatment of moderate‐to‐severe vasomotor symptoms (VMS) associated with menopause. Objective To compare the efficacy of elinzanetant with non‐hormonal pharmaceutical treatments (nHT) in alleviating VMS.
Piotr Wojciechowski, Klaudia Kolonko, Andromachi Giannopoulou, Beata Smela, Elżbieta Olewinska, Kristina Rosa Bolling, Jenifer Sassarini, Lee P. Shulman, Vikram Talaulikar   +8 more
wiley   +1 more source

Hormone Replacement Therapy for Menopausal Symptoms and the Risk of Cardiometabolic Disease: Current Evidence and Future Directions

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Background The transition through menopause is accompanied by a series of adverse metabolic changes which are associated with an increased risk of cardiometabolic disease, a major cause of mortality in women after midlife. Whilst the indication for menopausal hormone replacement therapy (HRT) is the control of menopausal symptoms ...
Jiawen Dong, Sarah Hillman, Sharon Dixon, Anupa Shah, Radha Venkatakrishnan, Jeremy W. Tomlinson   +5 more
wiley   +1 more source

Indications and Efficacy of Progestogen‐Monotherapy as Menopause Hormone Therapy: A Narrative Review

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Menopausal hormone therapy (MHT) remains the most effective treatment for vasomotor symptoms (VMS) and other manifestations of menopause; however, its use is limited in women with contraindications to oestrogen. Progestogen monotherapy, though historically underutilized, represents a viable alternative in this population. This narrative review
Chloe Thomas, Olivia Carere, Lauren Clarfield, Michelle Jacobson   +3 more
wiley   +1 more source

Impact of a Structured Caesarean Reduction Strategy on Perinatal Outcomes: A Retrospective Ecological Time‐Trend Study

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To evaluate the long‐term impact of a structured, multidisciplinary CS reduction strategy in a high‐complexity Italian hospital. Design Retrospective ecological time‐trend study. Setting Tertiary obstetric care Italian centre. Sample 28 577 deliveries, ≥ 22 weeks' gestation, from 2014 to 2024 were analysed.
Stefania Fieni, Giovanni Morganelli, Gabriella Maria Celora, Biancamaria Mastrandrea, Tullio Ghi   +4 more
wiley   +1 more source

Comparison of Definitions of Severe Maternal Morbidity: A National Cohort Study Using Administrative Data

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To understand agreement between definitions of severe maternal morbidity (SMM), the reasons for disagreement and the impact the outcome definition may have on the measurement of ethnic and socioeconomic inequalities. Design A national cohort study using administrative data. Setting The English National Health Service.
Ian Henderson, Dorothea Geddes‐Barton, Raph Goldacre, Marian Knight   +3 more
wiley   +1 more source

Vaginal Oestrogen Therapy for Postmenopausal Women Undergoing Prolapse Surgery: A Multicentre Double‐Blind Randomised Placebo‐Controlled Clinical Trial

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To determine whether vaginal oestrogen therapy improves outcomes after prolapse surgery in postmenopausal women. Design Double‐blind, randomised, placebo‐controlled trial with 12 month follow‐up. Setting Multicentre, 22 hospitals in the Netherlands.
Eva V. Vodegel, Krista van Rest, Leonie Speksnijder, Astrid Vollebregt, Albert Adriaanse, Eveline J. Roos, Franca Gerards, Wilbert Spaans, Marko Sikkema, Joggem Veen, Flora Vernooij, Marinus van der Ploeg, Jan‐Paul W. R. Roovers, the EVA Study Group, Alfredo L. Milani, Mirjam Weemhoff, Anne Damoiseaux, Heleen van Dongen, Marieke Mous, Pieternel Steures, Geerte van de Pol, Bart Broekman, Fernando Tjin Asjoe, Jolande van der Stege, Ronald Mouw, Ruben G. Duijnhoven   +25 more
wiley   +1 more source

Peritoneal Fluid‐Derived Small Extracellular Vesicle Proteins as Potential Biomarkers for Endometriosis: A Case–Control Study

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To demonstrate the presence of peritoneal fluid (PF)‐derived small extracellular vesicles (sEVs) in endometriosis and control samples, to characterise their protein content and to define endometriosis‐specific biomarkers within the sEV proteome. Design Case–control experimental study. Setting Academic endometriosis centre.
Hannah M. Nazri, Roman Fischer, Joel Steele, Sanjiv Manek, Kavita S. Subramaniam, Benedikt M. Kessler, Krina T. Zondervan, Thomas T. Tapmeier, Christian M. Becker   +8 more
wiley   +1 more source

From radical hysterectomy to radical surgery for deep endometriosis

Gynecology and Minimally Invasive Therapy, 2023
Chyi- Long Lee, Boom Ping Khoo, Kuan- Gen Huang   +2 more
doaj   +1 more source