Results 121 to 130 of about 32,822 (264)

Deep learning‐enhanced 3D imaging unveils semaglutide impact on cardiac fibrosis

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 5, Page 1030-1047, March 2026.
Background and Purpose Myocardial fibrosis (MF), a hallmark of structural cardiac remodelling, drives disease progression across most forms of heart failure and plays a central role in heart failure with preserved ejection fraction (HFpEF). Despite its clinical relevance, effective treatments remain scarce.
Sheyla Barrado‐Ballestero   +11 more
wiley   +1 more source

Radical Versus Partial Nephrectomy [PDF]

open access: yesHealth Affairs, 2015
Bruce L, Jacobs, Benjamin J, Davies
openaire   +2 more sources

Long‐acting insulin analogues and the risk of diabetic nephropathy among patients with type 2 diabetes: A population‐based cohort study

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 3, Page 2113-2122, March 2026.
Abstract Aims The risk of diabetic nephropathy among patients with type 2 diabetes (T2D) can be reduced through optimal glycaemic control. It is not known if the pharmacological properties of long‐acting insulin analogues may reduce the risk of diabetic complications compared with neutral protamine Hagedorn (NPH) insulin.
Julia Brillinger   +6 more
wiley   +1 more source

Oncogenic NRAS Mutation in Incipient Sarcomatous Transformation of Cystic Nephroma From a Patient With DICER1‐Related Tumor Predisposition Syndrome

open access: yesPediatric Blood &Cancer, Volume 73, Issue 2, February 2026.
ABSTRACT Anaplastic sarcoma of the kidney (ASK) is a DICER1‐associated malignant tumor presumed to arise in a benign precursor, pediatric cystic nephroma (PCN). However, the initial oncogenic alteration(s) associated with malignant transformation are unknown.
Nahir Cortes‐Santiago   +6 more
wiley   +1 more source

SETDB2 Mitigates Podocyte Dysfunction in Diabetic Kidney Disease Through Epigenetic Silencing of SMAD3

open access: yesAdvanced Science, Volume 13, Issue 9, 13 February 2026.
SETDB2 epigenetically represses Smad3 transcription by increasing H3K9me3 enrichment at its promoter, thereby mitigating podocyte dysfunction in DKD. The transcription factor TCF21 binds directly to the Setdb2 promoter and enhances its expression in podocytes. Abstract Podocyte dysfunction represents both an early pathological hallmark and a key driver
Lanfang Li   +14 more
wiley   +1 more source

Partial nephrectomy for presumed renal cell carcinoma: Incidence, predictors, and perioperative outcomes of benign lesions [PDF]

open access: yes, 2017
Bauman, Tyler M   +5 more
core   +2 more sources

Polystyrene Microplastics Exposure Aggravates Clear Cell Renal Cell Carcinoma Progression via the NF‐κB and TGF‐β Signaling Pathways

open access: yesAdvanced Science, Volume 13, Issue 8, 9 February 2026.
This research provides the first comprehensive evidence that PS‐MPs exacerbate ccRCC progression by activating the NF‐κB and TGF‐β pathways. These findings establish PS‐MPs as an environmental risk factor for ccRCC progression and identify the NF‐κB and TGF‐β signaling as potential therapeutic targets to mitigate the adverse effects of ‐PS‐MPs exposure.
Shiqi Ye   +18 more
wiley   +1 more source

ТранÑпериотонеална радикална нефректомија во третманот на карциномот на бубрег: компликации [PDF]

open access: yes, 2016
Ðаnравен е преглед на наашето хируршко иÑкуÑтво Ñо интра и поÑтоnеративните компликации, документирано кај 275 паци­ÐµÐ½Ñ‚и Ñо карциноми на бубрег
ПетровÑки, Д   +1 more
core   +1 more source

Racial and socioeconomic disparities from time of diagnosis to treatment for small renal masses

open access: yesBJUI Compass, Volume 7, Issue 2, February 2026.
Abstract Objectives To investigate how patient‐specific factors, including race and socioeconomic status, impact time to treatment initiation (TTI) for patients with small renal masses (SRMs). Materials and Methods We retrospectively reviewed 275 patients with SRMs ≤ 4 cm at Atrium Health Carolinas Medical Center who underwent treatment for their renal
Lila G. McGrath   +10 more
wiley   +1 more source

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