Results 101 to 110 of about 427,861 (368)

Circulating histones as clinical biomarkers in critically ill conditions

open access: yesFEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez   +17 more
wiley   +1 more source

The Dynamical Behavior of the s-Trioxane Radical Cation—A Low-Temperature EPR and Theoretical Study

open access: yesMolecules, 2014
The radical cation of s-trioxane, radiolytically generated in a freon (CF3CCl3) matrix, was studied in the 10–140 K temperature region. Reversible changes of the EPR spectra were observed, arising from both ring puckering and ring inversion through the ...
Sergej S. Naumov   +4 more
doaj   +1 more source

The Elusive 5'-Deoxyadenosyl Radical: Captured and Characterized by EPR and ENDOR Spectroscopies.

open access: yesJournal of the American Chemical Society, 2019
The 5'-deoxyadenosyl radical (5'-dAdo•) ab-stracts a substrate H-atom as the first step in radical-based transformations catalyzed by adenosylcobalamin-dependent and radical S-adenosyl-L-methionine (RS) enzymes.
Hao Yang   +8 more
semanticscholar   +1 more source

Unlocking the potential of tumor‐derived DNA in urine for cancer detection: methodological challenges and opportunities

open access: yesMolecular Oncology, EarlyView.
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever   +1 more
wiley   +1 more source

A Structure–Activity Relationship Study on the Antioxidant Properties of Dithiocarbamic Flavanones

open access: yesAntioxidants
The antioxidant properties of 3-dithiocarbamic flavanones have been investigated. The influence of the halogen substituents on ring A of the flavanones and the nature of the secondary amine from the dithiocarbamic moiety have been accounted.
Mihail Lucian Birsa   +1 more
doaj   +1 more source

Polyoxazoline-Based Bottlebrush and Brush-Arm Star Polymers via ROMP: Syntheses and Applications as Organic Radical Contrast Agents.

open access: yesACS Macro Letters, 2019
The synthesis of functional poly(2-alkyl-2-oxazoline) (PAOx) copolymers with complex nanoarchitectures using a graft-through ring-opening metathesis polymerization (ROMP) approach is described.
G. G. Alvaradejo   +9 more
semanticscholar   +1 more source

Subpar reporting of pre‐analytical variables in RNA‐focused blood plasma studies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical variables strongly influence the analysis of extracellular RNA (cell‐free RNA; exRNA) derived from blood plasma. Their reporting is essential to allow interpretation and replication of results. By evaluating 200 exRNA studies, we pinpoint a lack of reporting pre‐analytical variables associated with blood collection, plasma preparation ...
Céleste Van Der Schueren   +16 more
wiley   +1 more source

On radicals and polynomial rings

open access: yesPortugaliae Mathematica, 2008
For any class \mathcal M of rings, it is shown that the class \mathcal E_ℓ(\mathcal M) of all rings each non-zero homomorphic image of which contains either a non-zero left ideal in \mathcal M
Abish Mekei   +2 more
openaire   +2 more sources

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi   +3 more
wiley   +1 more source

Organocatalytic activation of cyclopropanes in asymmetric synthesis

open access: yesTetrahedron Chem, 2023
Cyclopropanes are strained carbocycles that can undergo ring opening reactions in which one of the C–C bond present in the cycle is broken following a radical or ionic mechanism.
Efraím Reyes   +4 more
doaj  

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