Results 121 to 130 of about 427,861 (368)

Cellular liquid biopsy provides unique chances for disease monitoring, preclinical model generation and therapy adjustment in rare salivary gland cancer patients

open access: yesMolecular Oncology, EarlyView.
We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić   +31 more
wiley   +1 more source

Circulating tumor DNA (ctDNA) trajectories predict survival in trifluridine/tipiracil‐treated metastatic colorectal cancer patients

open access: yesMolecular Oncology, EarlyView.
The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld   +7 more
wiley   +1 more source

Semi-radicals of Sub modules in Modules

open access: yesInternational Journal of Industrial Engineering and Production Research, 2008
: Let be a commutative ring and be a unitary module. We define a semiprime submodule of a module and consider various properties of it. Also we define semi-radical of a submodule of a module and give a number of its properties.
H. Tavallaee, R. Varmazyar
doaj   +2 more sources

Effects of geminal methyl groups on the tunnelling rates in the ring opening of cyclopropylcarbinyl radical at cryogenic temperature.

open access: yesOrganic and biomolecular chemistry, 2011
CVT + SCT calculations on the rate of tunnelling at 20 K in the ring opening of cyclopropylcarbinyl radical, substituted with geminal methyl groups at a ring carbon (1b), have been performed.
Xue Zhang   +3 more
semanticscholar   +1 more source

Integrative analysis of circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients: a comprehensive approach

open access: yesMolecular Oncology, EarlyView.
This study simultaneously investigated circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients. The elevated expression of JUNB and CXCR4 in CTCs was a poor prognostic factor for SCLC patients, whereas exosomal overexpression of these biomarkers revealed a high discrimination ability of patients from healthy individuals,
Dimitrios Papakonstantinou   +13 more
wiley   +1 more source

Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi   +26 more
wiley   +1 more source

On Semiabelian π-Regular Rings

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 2007
A ring R is defined to be semiabelian if every idempotent of R is either right semicentral or left semicentral. It is proved that the set N(R) of nilpotent elements in a π-regular ring R is an ideal of R if and only if R/J(R) is abelian, where J(R) is ...
Weixing Chen
doaj   +1 more source

A generalization of reflexive rings [PDF]

open access: yesMathematica Bohemica
We introduce a class of rings which is a generalization of reflexive rings and $J$-reversible rings. Let $R$ be a ring with identity and $J(R)$ denote the Jacobson radical of $R$.
Mete Burak Çalcı   +2 more
doaj   +1 more source

Recent progress on the synthesis of cyclic polymers via ring‐expansion strategies

open access: yes, 2017
Cyclic polymers are the simplest topological isomers of linear macromolecules, but exhibit properties that differ from linear chains in ways that remain imperfectly understood.
Young A. Chang, R. Waymouth
semanticscholar   +1 more source

Solution-phase mechanistic study and solid-state structure of a tris(bipyridinium radical cation) inclusion complex.

open access: yesJournal of the American Chemical Society, 2012
The ability of the diradical dicationic cyclobis(paraquat-p-phenylene) (CBPQT(2(•+))) ring to form inclusion complexes with 1,1'-dialkyl-4,4'-bipyridinium radical cationic (BIPY(•+)) guests has been investigated mechanistically and quantitatively.
A. Fahrenbach   +11 more
semanticscholar   +1 more source

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