Results 201 to 210 of about 89,695 (313)
Exploring 1,3,4-oxadiazolyl sulfide derivatives as antidiabetic candidates: synthesis, antioxidant activity, SAR-study, molecular docking, and DFT-insights. [PDF]
Khalaf NA +3 more
europepmc +1 more source
On the zeroid radical of a ring
openaire +2 more sources
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source
Metabolic Stability of Fluorinated Small Molecules: A Physical Organic Chemistry Perspective. [PDF]
Bhattarai P, Trombley TA, Altman RA.
europepmc +1 more source
This study investigates the protective role of salubrinal against heat‐induced endoplasmic reticulum (ER) stress in mouse spermatogenic cells (GC1 and GC2). By modulating the ER stress pathway, salubrinal alleviates cellular stress and supports spermatogenic cell survival, suggesting its potential as a therapeutic candidate for heat‐related infertility.
Suna Karadeniz Saygili +2 more
wiley +1 more source
Ring closures of aryl radicals / by Gordon Francis Meijs
Gordon F. Meijs
openalex +1 more source
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani +6 more
wiley +1 more source
Photochemical Macrolactonization of Hydroxyaldehydes via C-H Bromination. [PDF]
Kodaki S +4 more
europepmc +1 more source

