Results 81 to 90 of about 89,695 (313)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

ON THE PRIME RADICAL OF A MODULE OVER A NONCOMMUTATIVE RING

open access: yesTaiwanese Journal of Mathematics, 2004
In this paper all rings are associative with identity and all modules are unital left modules. Let \(M\) be a left \(R\)-module. A proper submodule \(N\) of \(M\) is called prime if, for any \(r\in R\) and \(m\in M\) such that \(rRm\subseteq N\), either \(rM\subseteq N\) or \(m\in N\). The prime radical \(\text{rad\,}M\) of a module \(M\) is defined to
Callialp, Fethic, Tekir, Unsal
openaire   +5 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

The weak radical of a ring [PDF]

open access: yesProceedings of the American Mathematical Society, 1967
Koh, Kwangil, Mewborn, A. C.
openaire   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

A generalization of reflexive rings [PDF]

open access: yesMathematica Bohemica
We introduce a class of rings which is a generalization of reflexive rings and $J$-reversible rings. Let $R$ be a ring with identity and $J(R)$ denote the Jacobson radical of $R$.
Mete Burak Çalcı   +2 more
doaj   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

On Semiabelian π-Regular Rings

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 2007
A ring R is defined to be semiabelian if every idempotent of R is either right semicentral or left semicentral. It is proved that the set N(R) of nilpotent elements in a π-regular ring R is an ideal of R if and only if R/J(R) is abelian, where J(R) is ...
Weixing Chen
doaj   +1 more source

Degradable Linear and Bottlebrush Thioester-Functional Copolymers through Atom-Transfer Radical Ring-Opening Copolymerization of a Thionolactone [PDF]

open access: hybrid, 2022
Qamar un Nisa   +6 more
openalex   +1 more source

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