Results 81 to 90 of about 89,695 (313)
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
ON THE PRIME RADICAL OF A MODULE OVER A NONCOMMUTATIVE RING
In this paper all rings are associative with identity and all modules are unital left modules. Let \(M\) be a left \(R\)-module. A proper submodule \(N\) of \(M\) is called prime if, for any \(r\in R\) and \(m\in M\) such that \(rRm\subseteq N\), either \(rM\subseteq N\) or \(m\in N\). The prime radical \(\text{rad\,}M\) of a module \(M\) is defined to
Callialp, Fethic, Tekir, Unsal
openaire +5 more sources
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
The weak radical of a ring [PDF]
Koh, Kwangil, Mewborn, A. C.
openaire +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
A generalization of reflexive rings [PDF]
We introduce a class of rings which is a generalization of reflexive rings and $J$-reversible rings. Let $R$ be a ring with identity and $J(R)$ denote the Jacobson radical of $R$.
Mete Burak Çalcı +2 more
doaj +1 more source
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
On Semiabelian π-Regular Rings
A ring R is defined to be semiabelian if every idempotent of R is either right semicentral or left semicentral. It is proved that the set N(R) of nilpotent elements in a π-regular ring R is an ideal of R if and only if R/J(R) is abelian, where J(R) is ...
Weixing Chen
doaj +1 more source
Degradable Linear and Bottlebrush Thioester-Functional Copolymers through Atom-Transfer Radical Ring-Opening Copolymerization of a Thionolactone [PDF]
Qamar un Nisa +6 more
openalex +1 more source

