Results 51 to 60 of about 146,011 (308)

Goodbye flat lymphoma biology

FEBS Letters, EarlyView.
Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria, Cèlia Dobaño‐López, Patricia Pérez‐Galán, Christine Bezombes   +3 more
wiley   +1 more source

Overview of Tacticity Control in Radical Polymerization

CHIMIA
The stereoregularity of a polymer plays a key role in determining its properties. While stereocontrol can easily be achieved in coordination and ionic polymerization, it remains a challenge with radical polymerization.
Hana Elhaddad, Daryl W. Yee
doaj   +1 more source

Constrained Nonlinear Model Predictive Control of an MMA Polymerization Process via Evolutionary Optimization

, 2014
In this work, a nonlinear model predictive controller is developed for a batch polymerization process. The physical model of the process is parameterized along a desired trajectory resulting in a trajectory linearized piecewise model (a multiple linear ...
Abbaszadeh, Masoud, Solgi, Reza
core   +1 more source

A multiswitchable poly(terthiophene) bearing a spiropyran functionality: understanding photo and electrochemical control [PDF]

, 2011
An electroactive nitrospiropyran-substituted polyterthiophene, 2-(3,3′′-dimethylindoline-6′-nitrobenzospiropyranyl)ethyl 4,4′′-didecyloxy-2,2′:5′,2′′-terthiophene-3′-acetate, has been synthesized for the first time.
Breukers, Robert, Byrne, Robert, Dennany, Lynn, Diamond, Dermot, Gambhir, Sanjeev, Higgins, Michael, Officer, David, Wagner, Klaudia, Wagner, Pawel, Wallace, Gordon, Zanoni, Michele   +10 more
core   +1 more source

The anabolic steroid stanozolol is a potent inhibitor of human MutT homolog 1

FEBS Letters, EarlyView.
MutT homolog 1 (MTH1) is a member of the NUDIX superfamily of enzymes and is an anticancer drug target. We show that stanozolol (Stz), an anabolic steroid, is an unexpected nanomolar inhibitor of MTH1. The X‐ray crystal structure of the human MTH1–Stz complex reveals a unique binding scaffold that could be utilized for future inhibitor development ...
Emma Scaletti Hutchinson, Robert Gustafsson Westergren, Ingrid Almlöf, Ann‐Sofie Jemth, Martin Scobie, Ulrika Warpman Berglund, Thomas Helleday, Pål Stenmark   +7 more
wiley   +1 more source

Organometallic mediated radical polymerization [PDF]

, 2012
Controlled radical polymerization has become increasingly important over the past decade and a half, allowing for the facile synthesis of specific macromolecular architectures with excellent control over the chemical and physical properties. This article
Allan, Laura E. N., Perry, Mitchell R., Shaver, Michael P.   +2 more
core   +1 more source

C‐mannosylation promotes ADAMTS1 activation and secretion in human testicular germ cell tumor NEC8 cells

FEBS Letters, EarlyView.
C‐mannosylation is a unique form of protein glycosylation. In this study, we demonstrated that ADAMTS1 is C‐mannosylated at Trp562 and Trp565 in human testicular germ cell tumor NEC8 cells. We found that C‐mannosylation of ADAMTS1 is essential for its secretion, processing, enzymatic activity, and ability to promote vasculogenic mimicry. These findings
Takato Kobayashi, Takehiro Suzuki, Ryota Kawahara, Natsumi Harai, Naoshi Dohmae, Siro Simizu   +5 more
wiley   +1 more source

Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes

FEBS Letters, EarlyView.
Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley   +1 more source

Thermal radical polymerization of Bis(methacrylamide)s

Polímeros
Methacrylamides monomers for dental applications were synthesized using a one-step procedure starting from methacrylic anhydride and the respective diamine: N,N’-(propane-1,3-diyl)-bis(N-ethyl-2-methylacrylamide) (1), N,N’-(butane-1,4-diyl)-bis(2 ...
Stéfani Becker Rodrigues, Fabrício Mezzomo Collares, Douglas Gamba, Vicente Castelo Branco Leitune, Cesar Liberato Petzhold   +4 more
doaj   +1 more source

The nicotinamide hypothesis revisited—plant defense signaling integrating PARP, nicotinamide, nicotinic acid, epigenetics, and glutathione

FEBS Letters, EarlyView.
Nicotinamide (NIC) and nicotinic acid (NIA) are proposed as stress signaling compounds in plants. Oxidative stress may lead to single strand breaks (SSB) in DNA, which activate poly(ADP‐ribose) polymerase (PARP). NIC and NIA are then formed from NAD. NIC and NIA can promote epigenetic changes leading to the expression of defense genes specific for the ...
Torkel Berglund, Anna B. Ohlsson
wiley   +1 more source