Results 61 to 70 of about 153,547 (331)

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

One-step volumetric additive manufacturing of complex polymer structures. [PDF]

, 2017
Two limitations of additive manufacturing methods that arise from layer-based fabrication are slow speed and geometric constraints (which include poor surface quality). Both limitations are overcome in the work reported here, introducing a new volumetric
Browar, Allison EM, Fang, Nicholas X, Henriksson, Johannes, Kelly, Brett E, Panas, Robert M, Shusteff, Maxim, Spadaccini, Christopher M, Weisgraber, Todd H   +7 more
core   +2 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Thermal radical polymerization of Bis(methacrylamide)s

Polímeros
Methacrylamides monomers for dental applications were synthesized using a one-step procedure starting from methacrylic anhydride and the respective diamine: N,N’-(propane-1,3-diyl)-bis(N-ethyl-2-methylacrylamide) (1), N,N’-(butane-1,4-diyl)-bis(2 ...
Stéfani Becker Rodrigues, Fabrício Mezzomo Collares, Douglas Gamba, Vicente Castelo Branco Leitune, Cesar Liberato Petzhold   +4 more
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Constrained Nonlinear Model Predictive Control of an MMA Polymerization Process via Evolutionary Optimization

, 2014
In this work, a nonlinear model predictive controller is developed for a batch polymerization process. The physical model of the process is parameterized along a desired trajectory resulting in a trajectory linearized piecewise model (a multiple linear ...
Abbaszadeh, Masoud, Solgi, Reza
core   +1 more source

Actin dynamics controlled by IqgC, a RasGAP at the crossroads between the IQGAP and fungal GAP1 families

FEBS Open Bio, EarlyView.
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić, Darija Putar, Lucija Mijanović, Igor Weber   +3 more
wiley   +1 more source

The synthesis of well-defined poly(vinylbenzyl chloride)-grafted nanoparticles via RAFT polymerization

Beilstein Journal of Organic Chemistry, 2013
We describe the use of one of the most advanced radical polymerization techniques, the reversible addition fragmentation chain transfer (RAFT) process, to produce highly functional core–shell particles based on a silica core and a shell made of ...
John Moraes, Kohji Ohno, Guillaume Gody, Thomas Maschmeyer, Sébastien Perrier   +4 more
doaj   +1 more source

Reversible addition fragmentation chain transfer polymerization - RAFT [PDF]

Hemijska Industrija, 2004
The fundamentals of controlled radical polymerization are presented in this review. The paper focuses on reversible addition fragmentation chain transfer (RAFT) polymerization.
Avramović Milena, Katsikas Lynne, Dunjić Branko, Popović Ivanka G.   +3 more
doaj   +1 more source

Profiling of oligolignols reveals monolignol coupling conditions in lignifying poplar xylem [PDF]

, 2004
Lignin is an aromatic heteropolymer, abundantly present in the walls of secondary thickened cells. Although much research has been devoted to the structure and composition of the polymer to obtain insight into lignin polymerization, the low-molecular ...
Boerjan, Wout, Goeminne, Geert, KIM, H, LU, FC, Messens, Eric, Morreel, Kris, RALPH, J, RALPH, S   +7 more
core   +3 more sources