Results 101 to 110 of about 1,225,901 (299)
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Hungary, Poland and Slovakia show the risks associated with mainstream parties co-opting the platforms of the radical right [PDF]
, 2015 The rise of the radical right has presented a challenge to mainstream parties in a number of European countries. As Bartek Pytlas writes, one of the strategies mainstream parties have adopted in several cases has been to co-opt the platforms of radical ...
Pytlas, Bartek
core
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Russians, Refugees and Europeans: What shapes the discourse of the Conservative People’s Party of Estonia? [PDF]
, 2017 The Conservative Peoples’ Party of Estonia (EKRE) presents a unique case in the study of far-right parties for two reasons. First, the ‘others’ to which they juxtapose Estonians are the Russian-speaking minority, who are white, Christian, and to a large ...
Wierenga, Louis
core +2 more sources
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Radical Right Parties of Contemporary Sweden
Vestnik MGIMO-Universiteta, 2011 .
E. G. Bolotnikova
doaj +1 more source
Surgical excision of renal cell carcinoma with caval and intra-atrial tumour thrombus extension using deep hypothermic circulatory arrest [PDF]
, 2013 Surgery for tumour thrombus extension in Renal Cell Carcinoma may be associated with a good prognosis if no distant metastases are identified and if the thrombus can be completely excised.
Bugeja, Simon +3 more
core
Right Move? Populist Radical Right Parties and Europe
The International SpectatorData access statement: This article analyses existing data as cited in the “References” section. While before winning power populist radical right (PRR) parties are often overtly against the European Union (EU) and its policies, once in government their position can change significantly.
Matilde Rosina +2 more
openaire +3 more sources
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source