Results 71 to 80 of about 195,053 (257)
FEBS Letters, EarlyView.Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Media and Communication, 2019 The Brexit referendum to leave the EU and Trump’s success in the US general election in 2016 sparked new waves of discussion on nativism, nationalism, and the far right.
Eviane Cheng Leidig
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
The Radical Right versus the Media: from Media Critique to Claims of (Mis)Representation
Politics and Governance, 2019 Criticizing mainstream media for their ‘lies’ or ‘fake news’ has become a common political practice on the radical right. Further empirical research is needed to better understand the intricacies of these attacks on media, in particular for the way they ...
Louise Knops, Benjamin De Cleen
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Journal of Social and Political PsychologyAlthough some scholars have associated cultural threats with radical right support and economic insecurities with radical left support, it has also been highlighted that economic insecurities might drive support for radical right movements.
Lucas Sudbrack, Peter Beattie
doaj +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Politics and GovernancePartisan affective polarization describes the extent to which different partisans like or dislike each other. In Europe, affective dislike is strongest towards the radical-right, as mainstream voters tend to hold particularly negative affect towards ...
Jochem Vanagt +3 more
doaj +1 more source