Results 51 to 60 of about 20,071 (223)

Lipid Nanoparticles Delivering ClpP‐mRNA Suppress Pyroptosis and Senescence in Intervertebral Disc Degeneration via mTOR/BNIP3‐Activated Mitophagy

Rare Metals, EarlyView.
ABSTRACT Intervertebral disc degeneration (IDD) is a predominant cause of low back pain, significantly impacting quality of life. Mitochondrial fitness is essential in the progression of IDD, as it regulates cellular senescence and pyroptosis. This study investigates the role of mitochondrial caseinolytic protease P (ClpP) in alleviating senescence and
Kun Wang, Zhiqiang Wang, Tong Zhang, Shicheng Qiu, Guang Yang, Yanzheng Gao, Xiaofeng Lian, Xin Peng   +7 more
wiley   +1 more source

Cervical Radicular Pain

, 2017
Cervical radicular pain is a common reason for patients in pain to seek care from a pain physician. Differing from low back pain and lumbar radiculopathy, cervical radicular pain is often not related to disc protrusion alone but, rather, a combination of disc and degenerative pathologies, such as uncovertebral hypertrophy and spondylosis. Likewise, the
Andrew I. Gitkind, Karina Gritsenko
openaire   +2 more sources

Epidural administration of anesthetics and corticosteroids in treatment of acute radicular pain syndrome of lumbar spine in neurosurgical department

Ukrainian Neurosurgical Journal, 2015
The purpose. To estimate efficacy of epidural administration corticosteroids and local anesthetics at radicular pain syndromes associated with discoradicular conflict in lumbar spine.Materials and methods. Epidural injection of corticosteroids
Valeriy Olkhov, O. Buyanov, Kostyantyn Horbatyuk, O. Kudina, Leonid Ventskivskiy, O. Borodenko, Volodymyr Kirichenko, Ivan Ventskivskiy, Iurii Chyrka, Ruslana Dolgopolova   +9 more
doaj   +1 more source

Case Report of Maxillary Alveolar Rhabdomyosarcoma Misdiagnosed as Periapical Lesion: Clinicopathological Alerts and Life‐Saving Lessons for Dentists

Australian Endodontic Journal, EarlyView.
ABSTRACT This report describes a rare case of alveolar rhabdomyosarcoma initially presenting with clinical features resembling an endodontic lesion. A 15‐year‐old male presented with progressive right maxillary swelling initially treated as a dental abscess.
Saliha Akçay Köprücü, Erdal Rahman Köprücü, Aysun Atasoy Sındıraç, Ümit Çobanoğlu   +3 more
wiley   +1 more source

Selective Root Canal Retreatment: A Scoping Review and Metasynthesis by Thematic Analysis

Australian Endodontic Journal, EarlyView.
ABSTRACT Selective root canal retreatment preserves well‐filled canals by treating only roots showing clinical or imaging evidence of failure, providing a minimally invasive alternative to conventional full retreatment. This scoping review, supported by metasynthesis through thematic analysis, synthesised clinical and imaging evidence in multirooted ...
José Evando da Silva‐Filho, Júlia Magalhães‐Saldanha, Ana Paula Caracas‐de‐Araújo, Zildenilson da Silva Sousa, Danielle Frota de Albuquerque, Eduardo Diogo Gurgel‐Filho   +5 more
wiley   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source

Analgesic effects of calcitonin on radicular pain in male rats

Journal of Pain Research, 2019
Yoshinori Terashima,1,2 Tsuneo Takebayashi,3 Shunsuke Jimbo,1 Izaya Ogon,1 Tatsuya Sato,2 Nobutoshi Ichise,2 Noritsugu Tohse,2 Toshihiko Yamashita1 1Department of Orthopaedic Surgery, School of Medicine, Sapporo Medical University, Sapporo 060-0061 ...
Terashima Y, Takebayashi T, Jimbo S, Ogon I, Sato T, Ichise N, Tohse N, Yamashita T   +7 more
doaj  

Persistent Sciatalgia due to a Wandering Bipolar Forceps Tip after Posterior Lumbar Stabilization: A Case Report

Indian Journal of Neurosurgery, 2016
There are several reports in the literature about the retained surgical materials as a cause of radicular pain or sensory impairment after spinal surgery. We report a patient with a persistent radicular pain in the distribution of left S1 nerve dermatome
Cengiz Gomleksiz, Mehmet Tokmak, Umut Yaka, Erhan Arslan, Muhammed Arif Özbek, S. Baki Albayrak   +5 more
doaj   +1 more source

Supraneural versus Infraneural Approach to transforaMinal Epidural StEroid injection for unilateral lumbosacral radicular pain (SIAMESE): a study protocol for a randomised non-inferiority trial

BJA Open, 2023
Background: Lumbosacral radicular pain is commonly treated by transforaminal steroid epidural injection. There are two methods: the supraneural and the infraneural approaches. The supraneural approach can result in rare but catastrophic consequences from
Helen F. Galley, Rosalind Adam, Malachy O. Columb, Uzunma M. Onyeakazi, Saravanakumar Kanakarajan   +4 more
doaj   +1 more source

Survival and Success of Teeth Involved in Alveolar Bone Injuries: Up to 10 Years of Follow‐Up

Dental Traumatology, EarlyView.
ABSTRACT Aim This study aimed to describe the epidemiological characteristics of patients with ABI treated at a specialized dental trauma center between 1998 and 2023; to analyze the survival rate of teeth involved in alveolar bone injuries (ABI) and assess the risks of healing outcomes for these teeth. Materials and Methods In total, 115 patients (367
Cristina Braga Xavier, Anthony Marcowich Rocha, Kerian Dorothy Rehbien, Lucas Borin Moura, Letícia Kirst Post, Kauê Collares   +5 more
wiley   +1 more source