Results 81 to 90 of about 25,712 (237)

Mendelian randomization analysis identifies HLA‐A and AP2M1 as genetic biomarkers linked to immune–endocytic crosstalk in intervertebral disc degeneration

Journal of Cell Communication and Signaling, Volume 20, Issue 1, March 2026.
HLA‐A and AP2M1 are identified as key endocytosis‐related biomarkers that modulate immune–endocytic crosstalk via mTOR signaling to regulate cell survival, immune infiltration, and the progression of intervertebral disc degeneration. Abstract Intervertebral disc degeneration (IVDD) is a major contributor to chronic spinal disorders, yet the role of ...
Yukui Tian, Xue Bai, Nianrong Han, Cheng Wang, Junchang Liu   +4 more
wiley   +1 more source

Proposal of a new anatomical landmark to identify the disc space in endoscopic lumbar discectomy

Journal of Craniovertebral Junction and Spine, 2019
Introduction: In endoscopic lumbar discectomy for posterolateral disc herniation, we determined some anatomical landmarks for improved disc space access.
Keyvan Mostofi, Morad Peyravi, Babak Gharaei Moghaddam, Reza Karimi Khouzani   +3 more
doaj   +1 more source

Expanding the Differential Diagnosis of Ultrasonographic Flexor Digitorum Profundus–Flexor Carpi Ulnaris Dissociation of Echogenicity: Muscular Dystrophies

Muscle &Nerve, Volume 73, Issue 3, Page 485-489, March 2026.
ABSTRACT Introduction/Aims Dissociation of echogenicity of the flexor digitorum profundus (FDP) and flexor carpi ulnaris (FCU) on neuromuscular ultrasound has been reported to be a useful sign to differentiate inclusion body myositis (IBM) from more common disease mimics, but it is not clear that this finding is pathognomonic of IBM. Our study aimed to
Anson W. Wilks, Nizar Chahin
wiley   +1 more source

A Literature Review: The Mechanisms and Treatment of Neuropathic Pain—A Brief Discussion

Biomedicines
Classically, neuropathic pain is described as a pain caused by a lesion or disease of the somatosensory system. However, one must note that the presence of somatosensory pathology alone does not guarantee a progression to neuropathic pain.
Renira Rugnath, Casey Orzechowicz, Clayton Newell, Veronica Carullo, Anesh Rugnath   +4 more
doaj   +1 more source

Bridging FDA Adverse Event Reporting System (FAERS) and Clinical Practice: Comprehensive Characterization of Immune Checkpoint Inhibitors Toxicities in Geriatric Lung Cancer Patients

Thoracic Cancer, Volume 17, Issue 6, March 2026.
Elderly lung cancer patients face increased risks of severe and fatal AEs during ICIs treatment. Reports concerning males, Asians, and anti‐PD‐1 recipients were associated with higher odds of a fatal outcome. Immune‐mediated pneumonitis is the most frequently reported severe AE, calling for heightened vigilance for these high‐risk subgroups.
Yumeng Tian, Xin Nie, Yue Yuan, Qian Wei, SiQi Zhang, Lin Li   +5 more
wiley   +1 more source

Effectiveness of Acupotomy Combined with Epidural Steroid Injection for Lumbosacral Radiculopathy: A Randomized Controlled Pragmatic Pilot Study

Medicina
Background and Objectives: This pilot study aimed to evaluate the clinical effectiveness, cost-effectiveness, and safety of acupotomy combined with epidural steroid injection (ESI) in lumbosacral radiculopathy and examine its feasibility for the main ...
Jin-Hyun Lee, Sang-Hyun Lee, Hae Sun Suh, Man-Suk Hwang, Semin Jang, Sooil Choi, Young-Soo Lim, Sang Hyun Byun, Sang-Hoon Yoon, Sukhee Park, Tae-Yong Park   +10 more
doaj   +1 more source

Structural and clinikal displays of discogenic radiculopathy in combination with haemangioma of spine [PDF]

Саратовский научно-медицинский журнал, 2010
The work presents the examination results of 104 patients with the symptoms of lumbosacral compressive radiculopathy. The intensity of pain syndrome at rest, in physical exertion and at night was assessed by visual analogue and verbal assessment scales ...
Fomina AM, Bugaeva I.O., Salina E.A., Sholomov I.I.   +3 more
doaj  

Congestive radiculopathy [PDF]

Neurology, 2008
Simon N, Jacob, Till, Diergarten, Arthur, Melms   +2 more
openaire   +2 more sources

Muscle MRI and Muscle Ultrasound Applications in MND/ALS: Academic Insights and Clinical Opportunities

European Journal of Neurology, Volume 33, Issue 3, March 2026.
ABSTRACT Background There is an unmet need for the clinically relevant ALS biomarkers to facilitate an accurate diagnosis in suspected cases, monitor disease progression and evaluate response to therapy in clinical trials. While the MND/ALS literature is dominated by innovative brain studies, motor disability in ALS is primarily driven by neurogenic ...
Alison Toomey, Jana Kleinerova, Ee Ling Tan, We Fong Siah, Peter Bede   +4 more
wiley   +1 more source

Nerve Conduction Study (NCS) in Patients with Cervical Radiculopathy at Arifin Achmad General Hospital, Riau Province

Frontiers on Healthcare Research
Background: Radiculopathy is one of the most common causes of neck pain in everyday clinical practice. Radiculopathy can occur in the cervical segment. The prevalence of cervical radiculopathy is lower than lumbar radiculopathy.
Riki Sukiandra, Azzahra Nur Aulya Putri, Desby Juananda, Yossi Maryanti   +3 more
doaj