Results 61 to 70 of about 27,167 (293)

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

FEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi, Shunsuke Morioka, Keiko Morisawa, Kazutsugu Matsukawa, Shingo Ashida, Takeshi Suzuki, Shuji Sakamoto   +6 more
wiley   +1 more source

Nonparametric Bayesian Filtering for Location Estimation, Position Tracking, and Global Localization of Mobile Terminals in Outdoor Wireless Environments

EURASIP Journal on Advances in Signal Processing, 2008
The mobile terminal positioning problem is categorized into three different types according to the availability of (1) initial accurate location information and (2) motion measurement data.Location estimation refers to the mobile positioning problem when
Mohamed Khalaf-Allah
doaj   +1 more source

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source

An Innovative Approach to Teaching Environmental Education Through Mind-Mapping and Creating Radio Programming

Discourse and Communication for Sustainable Education
The primary aims of environmental education and courses at universities are for students to develop an environmental mentality and to be able to apply that mindset to solving real-world issues.
Uyulgan Melis Arzu, Güven Nalan Akkuzu
doaj   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

Towards Cooperative Global Mapping of the Ionosphere: Fusion Feasibility for IGS and IRI with Global Climate VTEC Maps

Remote Sensing, 2020
Recommendations of the International Reference Ionosphere (IRI) Workshop 2017 in Taoyuan City, Taiwan and International GNSS Service (IGS) Workshop 2018 in Wuhan, China included establishment of an ionosphere mapping service that would fuse measurements ...
Adam Froń, Ivan Galkin, Andrzej Krankowski, Dieter Bilitza, Manuel Hernández-Pajares, Bodo Reinisch, Zishen Li, Kacper Kotulak, Irina Zakharenkova, Iurii Cherniak, David Roma Dollase, Ningbo Wang, Paweł Flisek, Alberto García-Rigo   +13 more
doaj   +1 more source

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

FEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao, Daiki Kobayashi, Shogo Hori, Osamu Saitoh   +3 more
wiley   +1 more source

Deep Learning–Assisted Differentiation of Four Peripheral Neuropathies Using Corneal Confocal Microscopy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Peripheral neuropathies contribute to patient disability but may be diagnosed late or missed altogether due to late referral, limitation of current diagnostic methods and lack of specialized testing facilities. To address this clinical gap, we developed NeuropathAI, an interpretable deep learning–based multiclass classification ...
Chaima Ben Rabah, Ioannis N. Petropoulos, Mark Stettner, Maryam Ferdousi, Uazman Alam, Nathan Efron, Ahmed Serag, Rayaz A. Malik   +7 more
wiley   +1 more source

Predicting Epileptogenic Tubers in Patients With Tuberous Sclerosis Complex Using a Fusion Model Integrating Lesion Network Mapping and Machine Learning

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Accurate localization of epileptogenic tubers (ETs) in patients with tuberous sclerosis complex (TSC) is essential but challenging, as these tubers lack distinct pathological or genetic markers to differentiate them from other cortical tubers.
Tinghong Liu, Qi Wang, Suhui Kuang, Dezhi Cao, Ping Ding, Shaohui Zhang, Haihua Wei, Zhirong Wei, Jinshan Xu, Xinyu Huang, Bing Liu, Shuli Liang   +11 more
wiley   +1 more source

Fingerprinting Database Development Methods for Reconfigurable Intelligent Surface Assisted Indoor Positioning System

IEEE Access
The positioning accuracy of a reconfigurable intelligent surface (RIS) assisted indoor positioning system (IPS) can be improved by developing a fingerprinting database for different RIS configurations.
Aisha Javed, Naveed Ul Hassan, Ammar Rafique, Muhammad Zubair, Marco Di Renzo, Chau Yuen   +5 more
doaj   +1 more source