Results 41 to 50 of about 286,691 (306)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Magnetic location of a possible earthquake epicentre area: a mathematical model

open access: yesGeomatics, Natural Hazards & Risk, 2016
We study one of the problems of the theory of seismo-electromagnetic methods of earthquake prediction, namely, the physical nature of magnetic location of a future epicentre.
O.B. Novik   +3 more
doaj   +1 more source

Effects of the ISM on Detection of Low-frequency Gravitational Waves

open access: yes, 2013
Time variable delays due to radio wave propagation in the ionized interstellar medium are a substantial source of error in pulsar timing array efforts.
Stinebring, Dan
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Ionosphere disturbance during cosmodrome “Vostochniy” launches

open access: yesE3S Web of Conferences, 2018
It is known that during spacecraft launches ionospheric plasma properties are modified in the result of impact of shock-acoustic waves generated during carrier rocket supersonic motion. As a rule, investigation of ionospheric plasma variations is carried
Dumbrava Zinaida F.   +3 more
doaj   +1 more source

J1128+592: a highly variable IDV source

open access: yes, 2007
Short time-scale radio variations of compact extragalactic radio quasars and blazars known as IntraDay Variability (IDV) can be explained in at least some sources as a propagation effect; the variations are interpreted as scintillation of radio waves in ...
Agudo   +28 more
core   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Recurrent and sporadic Forbush decreases during solar cycles 23–24

open access: yesSolar-Terrestrial Physics, 2019
A comparison has been made between recurrent (associated with high-speed streams from coronal holes) and sporadic (caused by interplanetary coronal mass ejections (ICMEs)) Forbush decreases (FDs) in solar cycles 23 and 24 (as well as in the maxima of ...
Melkumyan A.A.   +6 more
doaj   +1 more source

Methods and Algorithms of Subsurface Holographic Sounding

open access: yesRemote Sensing, 2022
In our experiments, we develop and test portable multi-element receiver antenna arrays, electrically scanned in order to immediately obtain a recognizable image of subsurface objects.
A. V. Popov   +5 more
doaj   +1 more source

The Radiation Transfer at a Layer of Magnetized Plasma With Random Irregularities [PDF]

open access: yes, 1998
The problem of radio wave reflection from an optically thick plane monotonous layer of magnetized plasma is considered at present work. The plasma electron density irregularities are described by spatial spectrum of an arbitrary form.
A G Bronin   +8 more
core   +2 more sources

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