Results 71 to 80 of about 93,637 (312)

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

open access: yesFEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori   +8 more
wiley   +1 more source

The Cosmic Evolution of Fast Radio Bursts Inferred from the CHIME/FRB Baseband Catalog 1

open access: yesThe Astrophysical Journal
Redshift and luminosity distributions are essential for understanding the cosmic evolution of extragalactic objects and phenomena, such as galaxies, gamma-ray bursts, and fast radio bursts (FRBs).
Om Gupta   +3 more
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

The Variability of Persistent Radio Sources of Fast Radio Bursts

open access: yesThe Astrophysical Journal
Over 700 bright millisecond-duration radio transients, known as fast radio bursts (FRBs), have been identified to date. Nevertheless, the origin of FRBs remains unknown.
Ai Yuan Yang   +15 more
doaj   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

open access: yesFEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu   +5 more
wiley   +1 more source

A Deep VLA Search for a Persistent Radio Counterpart to the One-off FRB 20250316A

open access: yesThe Astrophysical Journal Letters
Fast radio burst (FRB) 20250316A, detected by CHIME on 2025 March 16 with a fluence of 1.7 ± 0.1 kJy ms and a dispersion measure of 161.3 ± 0.4 pc cm ^−3 , ranks among the brightest extragalactic FRBs at ∼40 Mpc. We obtain deep Karl G.
Tao An   +6 more
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Methods and Algorithms of Wide Band Radiomonitoring under Small Element Antenna Arrays

open access: yesИзвестия высших учебных заведений России: Радиоэлектроника, 2016
Methods of panoramic radiomonitoring and developed on their basis algorithms for joint detection and direction finding in a wide band of frequencies are presented. The block diagrams and panoramas illustrating the results of the algorithms are given.
D. O. Zadirako   +5 more
doaj  

The role of lipid metabolism in neuronal senescence

open access: yesFEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari   +2 more
wiley   +1 more source

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